肝内胆管癌的传统、功能和放射组学评估

Conventional, functional and radiomics assessment for intrahepatic cholangiocarcinoma.

作者信息

Granata Vincenza, Fusco Roberta, Belli Andrea, Borzillo Valentina, Palumbo Pierpaolo, Bruno Federico, Grassi Roberta, Ottaiano Alessandro, Nasti Guglielmo, Pilone Vincenzo, Petrillo Antonella, Izzo Francesco

机构信息

Division of Radiology, "Istituto Nazionale Tumori IRCCS Fondazione Pascale - IRCCS di Napoli", 80131, Naples, Italy.

Medical Oncology Division, Igea SpA, Napoli, Italy.

出版信息

Infect Agent Cancer. 2022 Mar 28;17(1):13. doi: 10.1186/s13027-022-00429-z.

BACKGROUND

This paper offers an assessment of diagnostic tools in the evaluation of Intrahepatic Cholangiocarcinoma (ICC).

METHODS

Several electronic datasets were analysed to search papers on morphological and functional evaluation in ICC patients. Papers published in English language has been scheduled from January 2010 to December 2021.

RESULTS

We found that 88 clinical studies satisfied our research criteria. Several functional parameters and morphological elements allow a truthful ICC diagnosis. The contrast medium evaluation, during the different phases of contrast studies, support the recognition of several distinctive features of ICC. The imaging tool to employed and the type of contrast medium in magnetic resonance imaging, extracellular or hepatobiliary, should change considering patient, departement, and regional features. Also, Radiomics is an emerging area in the evaluation of ICCs. Post treatment studies are required to evaluate the efficacy and the safety of therapies so as the patient surveillance.

CONCLUSIONS

Several morphological and functional data obtained during Imaging studies allow a truthful ICC diagnosis.

背景

本文对肝内胆管癌（ICC）评估中的诊断工具进行了评估。

方法

分析了多个电子数据集，以查找有关ICC患者形态学和功能评估的论文。已安排检索2010年1月至2021年12月发表的英文论文。

结果

我们发现88项临床研究符合我们的研究标准。几个功能参数和形态学要素有助于进行准确的ICC诊断。在对比研究的不同阶段进行的造影剂评估有助于识别ICC的几个独特特征。考虑到患者、科室和区域特征，磁共振成像中使用的成像工具和造影剂类型（细胞外或肝胆特异性）应有所不同。此外，放射组学是ICC评估中一个新兴的领域。需要进行治疗后研究以评估治疗的疗效和安全性以及患者监测情况。