Brigham and Women's Hospital, Boston, USA.
Harvard Medical School, Boston, USA.
Dig Dis Sci. 2022 May;67(5):1674-1687. doi: 10.1007/s10620-022-07393-z. Epub 2022 Mar 29.
Obesity is pandemic. It is estimated that by 2030, half of the U.S. population will have obesity. Current treatment options for obesity includes lifestyle modification, pharmacotherapy, endoscopic bariatric and metabolic therapy (EBMT) and bariatric surgery. Over the past decades, an increasing number of EBMTs have been developed and become available. As a gastroenterologist, it is therefore important to become familiar with the available EBMTs as well as their safety and efficacy profiles in order to educate and expeditiously refer patients for the appropriate therapy when eligible. This chapter will review currently available and upcoming EBMTs. Details on how the procedures are performed, their mechanisms of action as well as data from pivotal studies will be summarized.
肥胖是全球性的问题。据估计,到 2030 年,美国将有一半的人口肥胖。目前肥胖症的治疗方法包括生活方式改变、药物治疗、内镜减重和代谢治疗(EBMT)以及减重手术。在过去的几十年中,已经开发出越来越多的 EBMT 并得到了应用。因此,作为一名胃肠病学家,熟悉现有的 EBMT 及其安全性和疗效特征非常重要,以便在符合条件时为患者提供适当的治疗并进行教育和快速转介。本章将回顾目前可用的和即将出现的 EBMT。将总结手术的详细信息、作用机制以及主要研究的数据。