Department of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, USA.
School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Chem Soc Rev. 2022 May 10;51(9):3380-3435. doi: 10.1039/d1cs00858g.
The development of flexible piezoelectric nanogenerators has experienced rapid progress in the past decade and is serving as the technological foundation of future state-of-the-art personalized healthcare. Due to their highly efficient mechanical-to-electrical energy conversion, easy implementation, and self-powering nature, these devices permit a plethora of innovative healthcare applications in the space of active sensing, electrical stimulation therapy, as well as passive human biomechanical energy harvesting to third party power on-body devices. This article gives a comprehensive review of the piezoelectric nanogenerators for personalized healthcare. After a brief introduction to the fundamental physical science of the piezoelectric effect, material engineering strategies, device structural designs, and human-body centered energy harvesting, sensing, and therapeutics applications are also systematically discussed. In addition, the challenges and opportunities of utilizing piezoelectric nanogenerators for self-powered bioelectronics and personalized healthcare are outlined in detail.
在过去的十年中，柔性压电纳米发电机的发展取得了飞速的进步，它是未来先进个性化医疗保健的技术基础。由于其高效的机械能-电能转换、易于实现和自供电的特性，这些设备在主动传感、电刺激治疗以及被动人体生物力学能量收集等领域为创新的医疗保健应用提供了可能，可将第三方电源应用于人体设备上。本文对用于个性化医疗保健的压电纳米发电机进行了全面的回顾。在简要介绍压电效应的基本物理科学、材料工程策略、器件结构设计以及以人体为中心的能量收集、传感和治疗应用之后，还系统地讨论了这些应用。此外，还详细概述了利用压电纳米发电机实现自供电生物电子学和个性化医疗保健的挑战和机遇。
