Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
J Nat Med. 2022 Jun;76(3):680-685. doi: 10.1007/s11418-022-01621-6. Epub 2022 Mar 30.
Feruloylated acylglycerols (FAGs) have recently garnered a lot of interest as water-oil-miscible ferulic acid derivatives. A novel FAG derivate, 1-feruloyl-3-hexadecanoylglycerol (1), was isolated from Wikstroemia pilosa and its structure was elucidated from extensive physiochemical and spectroscopic analysis. Since the limited distribution of FAGs in plant species has been reported, a high-resolution accurate mass (HRAM) LC-MS quantitative analysis was carried out to determine the contents of 1 in ten plants of Wikstroemia species. As a result, compound 1 was detected in all species at contents of 1.29-50.96 mg/kg dry weight and W. dolichantha contained 1 at the highest content.
阿魏酰基甘油酯(FAGs)作为亲油亲水性阿魏酸衍生物,近来受到广泛关注。从密花斜萼麻中分离得到一种新型 FAG 衍生物 1-阿魏酰基-3-十六烷酰基甘油(1),通过广泛的理化和光谱分析阐明了其结构。由于 FAGs 在植物物种中的分布有限,因此进行了高分辨率精确质量(HRAM)LC-MS 定量分析,以确定密花斜萼麻属的十种植物中 1 的含量。结果,在所有物种中均检测到化合物 1,含量为 1.29-50.96mg/kg 干重,密花斜萼麻中的含量最高。