Gumbita Robert, Liu Jason Z, Prasad Rohan Madhu, Radwan Yasser, Nabeel Muhammad
Department of Internal Medicine, Michigan State University, Sparrow Hospital, Lansing, MI.
Ochsner J. 2022 Spring;22(1):85-88. doi: 10.31486/toj.21.0030.
The common dermatologic manifestations seen in patients with coronavirus disease 2019 (COVID-19) include morbilliform, pernio-like, urticarial, macular erythematous, vesicular, and papulosquamous disorders, as well as retiform purpura. Although cases of acro-ischemia have been demonstrated, they are not well studied or reported. A 73-year-old male was admitted for acute hypoxic respiratory failure secondary to COVID-19 infection. During the patient's hospital course, his oxygen requirement progressively increased, and he developed painful, violaceous purpura on his right lower extremity digits. The patient was treated with therapeutic doses of enoxaparin and nitroglycerin ointment in the hospital and apixaban on discharge. The patient was lost to follow-up. The multiorgan dysfunction associated with COVID-19 includes dermatologic manifestations. This case illustrates that acro-ischemia can resolve with guideline-based medical treatment.
2019冠状病毒病（COVID-19）患者常见的皮肤表现包括麻疹样、冻疮样、荨麻疹样、斑疹性红斑、水疱性和丘疹鳞屑性疾病，以及网状紫癜。尽管已经证实存在肢端缺血病例，但对其研究和报道并不充分。一名73岁男性因COVID-19感染继发急性低氧性呼吸衰竭入院。在患者住院期间，其氧气需求逐渐增加，右下肢趾端出现疼痛性紫蓝色紫癜。患者在医院接受了治疗剂量的依诺肝素和硝酸甘油软膏治疗，出院时服用阿哌沙班。患者失访。与COVID-19相关的多器官功能障碍包括皮肤表现。该病例表明，基于指南的药物治疗可使肢端缺血得到缓解。
