Section of Hygiene, University Department of Life Sciences and Public Health; Catholic University of the Sacred Heart, Rome, Italy.
VIHTALI (Value In Health Technology and Academy for Leadership & Innovation), Spin-Off of Università Cattolica del Sacro Cuore, Rome, Italy.
Front Public Health. 2022 Mar 9;10:786662. doi: 10.3389/fpubh.2022.786662. eCollection 2022.
To provide a new value-based immunization approach collating the available scientific evidence on the topic.
Four value pillars (personal, allocative, technical, and societal) applied to vaccination field were investigated. A systematic literature review was performed querying three database from December 24th, 2010 to May 27th, 2020. It included studies on vaccine-preventable diseases (VPDs) that mentioned the term value in any part and which were conducted in advanced economies. An in-depth analysis was performed on studies addressing value as key element.
Overall, 107 studies were considered. Approximately half of the studies addressed value as a key element but in most of cases (83.3%) only a single pillar was assessed. Furthermore, the majority of papers addressed the technical value by looking only at classical methods for economic assessment of vaccinations whereas very few dealt with societal and allocative pillars.
Estimating the vaccinations value is very complex, even though their usefulness is certain. The assessment of the whole value of vaccines and vaccinations is still limited to some domains and should encompass the wider impact on economic growth and societies.
提供一种新的基于价值的免疫方法，整理该主题的现有科学证据。
研究了适用于疫苗接种领域的四个价值支柱（个人、分配、技术和社会）。从 2010 年 12 月 24 日至 2020 年 5 月 27 日，通过查询三个数据库进行了系统文献回顾。它包括在发达经济体中提到疫苗可预防疾病（VPD）中任何部分的术语价值的研究。对将价值作为关键要素的研究进行了深入分析。
总共考虑了 107 项研究。大约一半的研究将价值作为一个关键要素，但在大多数情况下（83.3%）仅评估了一个支柱。此外，大多数论文通过仅使用评估疫苗接种的经典经济评估方法来研究技术价值，而很少涉及社会和分配支柱。
尽管疫苗的效用是确定的，但评估疫苗接种的价值非常复杂。对疫苗整体价值的评估仍仅限于某些领域，应包括对经济增长和社会的更广泛影响。
