Departamento de Zootecnia, Universidade Federal da Paraíba, Areia, Paraíba, Brazil.
Embrapa Southeast Livestock, São Carlos, São Paulo, Brazil.
PLoS One. 2022 Apr 1;17(4):e0264279. doi: 10.1371/journal.pone.0264279. eCollection 2022.
Analyses of livestock genomes have been used to detect selection signatures, which are genomic regions associated with traits under selection leading to a change in allele frequency. The objective of the present study was to characterize selection signatures in Canchim composite beef cattle using cross-population analyses with the founder Nelore and Charolais breeds. High-density single nucleotide polymorphism genotypes were available on 395 Canchim representing the target population, along with genotypes from 809 Nelore and 897 Charolais animals representing the reference populations. Most of the selection signatures were co-located with genes whose functions agree with the expectations of the breeding programs; these genes have previously been reported to associate with meat quality, as well as reproductive traits. Identified genes were related to immunity, adaptation, morphology, as well as behavior, could give new perspectives for understanding the genetic architecture of Canchim. Some selection signatures identified genes that were recently introduced in Canchim, such as the loci related to the polled trait.
利用家畜基因组分析已经能够检测到选择信号，这些信号与受选择影响的特征相关，导致等位基因频率发生变化。本研究的目的是利用与创始品种内罗尔牛和夏洛莱牛的交叉群体分析来描述坎钦姆复合肉牛的选择信号。在目标群体中，有 395 头坎钦姆牛的高密度单核苷酸多态性基因型，以及 809 头内罗尔牛和 897 头夏洛莱牛的参考群体基因型。大多数选择信号与基因的功能相一致，这些基因与肉质以及生殖性状有关；这些基因之前曾被报道与肉质以及生殖性状有关。鉴定出的基因与免疫、适应、形态以及行为有关，这为理解坎钦姆的遗传结构提供了新的视角。一些选择信号鉴定出了最近引入坎钦姆的基因，如与无角性状相关的基因座。
