College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Arch Osteoporos. 2022 Apr 2;17(1):56. doi: 10.1007/s11657-022-01085-x.
A prospective hospital-based survey in representative regions of Saudi Arabia determined the incidence of fractures at the hip. The hip fracture rates were used to create a FRAX® model to facilitate fracture risk assessment in Saudi Arabia.
This paper describes the incidence of hip fracture in the Kingdom of Saudi Arabia that was used to characterize the current and future burden of hip fracture, to develop a country-specific FRAX® tool for fracture prediction and to compare fracture probabilities with neighbouring countries.
During a 2-year (2017/2018) prospective survey in 15 hospitals with a defined catchment population, hip fractures in Saudi citizens were prospectively identified from hospital registers. The number of hip fractures and future burden was determined from national demography. Age- and sex-specific incidence of hip fracture and national mortality rates were incorporated into a FRAX model for Saudi Arabia. Fracture probabilities were compared with those from Kuwait and Abu Dhabi.
The incidence of hip fracture applied nationally suggested that the estimated number of hip fractures nationwide in persons over the age of 50 years for 2015 was 2,949 and is predicted to increase nearly sevenfold to 20,328 in 2050. Hip fracture rates were comparable with estimates from Abu Dhabi and Kuwait. By contrast, probabilities of a major osteoporotic fracture or hip fracture from the age of 70 years were much lower than those seen in Abu Dhabi and Kuwait due to higher mortality estimates for Saudi Arabia.
A country-specific FRAX tool for fracture prediction has been developed for Saudi Arabia which is expected to help guide decisions about treatment.
本研究旨在描述沙特阿拉伯的髋部骨折发病率,用于描述当前和未来髋部骨折负担,为沙特阿拉伯开发一种特定于国家的 FRAX®工具以预测骨折,并与邻国的骨折概率进行比较。
在为期 2 年(2017/2018 年)的 15 家医院的前瞻性调查中,使用定义的集水区人群,从医院登记处前瞻性地确定沙特公民的髋部骨折。髋部骨折的数量和未来负担是根据国家人口统计学确定的。将年龄和性别特异性髋部骨折发病率和国家死亡率纳入沙特阿拉伯的 FRAX 模型。比较了骨折概率与科威特和阿布扎比的骨折概率。
全国范围内髋部骨折的发病率表明,2015 年全国 50 岁以上人群的髋部骨折估计数为 2949 例,预计到 2050 年将增加近 7 倍,达到 20328 例。髋部骨折发生率与阿布扎比和科威特的估计值相当。相比之下,由于沙特阿拉伯的死亡率估计较高,70 岁及以上人群发生主要骨质疏松性骨折或髋部骨折的概率远低于阿布扎比和科威特。
为沙特阿拉伯开发了一种特定于国家的 FRAX®骨折预测工具,预计将有助于指导治疗决策。