Yakupu Aobuliaximu, Wang Hanqi, Huang Lifang, Zhou Jingqi, Wu Fangyi, Lu Yong, Lu Shuliang
Wound Healing Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, China.
Department of Burn, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, China.
Int J Low Extrem Wounds. 2025 Jun;24(2):355-366. doi: 10.1177/15347346221092265. Epub 2022 Apr 5.
Pressure ulcer (PU) is a type of chronic ulcer, placing a high burden not only on patients' families but also on national healthcare systems globally. To determine the level, trends, and burden of PU worldwide and to provide an essential foundation for building targeted public policies on PUs at the national, regional, and global levels, data on PU were obtained from the Global Burden of Disease (GBD) 2019 Study. The incidence, disability-adjusted life years (DALYs), and deaths of PUs in 204 countries and regions from 1990 to 2019 were calculated and stratified by sex, age, geographical location, and sociodemographic index (SDI). The estimated annual percentage change (EAPC) of incidence, DALYs, and deaths was calculated to evaluate the temporal trends. A total of 3,170,796 new cases (95% uncertainty interval (UI), 3,499,729-2,875,433 cases) of PU were identified globally in 2019, more than 55% of which were among male individuals, and most of the new cases were concentrated in those 75-90 years of age. The burden of PU measured in DALYs was 481 423 (95% UI, 583 429-374 334) in 2019, 73% and 27% of which could be attributed to years of life lost (YLLs) and years lived with disability (YLDs), respectively. The burden increased gradually from 1990 to 2019 (from 267 846 [360 562-211 024] to 481 423 [95% UI, 583 429-374 334]). A total of 24 389 deaths were attributed to PU (95% UI, 31 260.82-17 299). The EAPC of incidence, DALYs, and deaths were negative in most regions, the age-standardized rate (ASR) of incidence, DALYs, and deaths were considered to be decreasing in most of the regions, and the EAPCs were negatively correlated with the SDI levels, universal health coverage (UHC), and gross domestic product (GDP), which shows that the ASRs of PU decreased as the economy developed and countries' healthcare system performances improved.
压疮（PU）是一种慢性溃疡，不仅给患者家庭带来沉重负担，也给全球各国的医疗保健系统造成了巨大压力。为了确定全球压疮的水平、趋势和负担，并为在国家、区域和全球层面制定针对性的压疮公共政策提供重要依据，我们从《2019年全球疾病负担（GBD）研究》中获取了压疮相关数据。计算了1990年至2019年期间204个国家和地区压疮的发病率、伤残调整生命年（DALYs）和死亡人数，并按性别、年龄、地理位置和社会人口指数（SDI）进行分层。计算发病率、DALYs和死亡人数的估计年变化百分比（EAPC）以评估时间趋势。2019年全球共确诊3170796例新的压疮病例（95%不确定区间（UI），3499729 - 2875433例），其中超过55%为男性，大多数新病例集中在75 - 90岁人群中。2019年以DALYs衡量的压疮负担为481423（95% UI，583429 - 374334），其中73%和27%分别可归因于生命损失年数（YLLs）和残疾生存年数（YLDs）。从1990年到2019年，负担逐渐增加（从267846 [360562 - 211024]增至481423 [95% UI，583429 - 374334]）。共有24389例死亡归因于压疮（95% UI，31260.82 - 17299）。大多数地区发病率、DALYs和死亡人数的EAPC为负，大多数地区发病率、DALYs和死亡人数的年龄标准化率（ASR）被认为在下降，且EAPC与SDI水平、全民健康覆盖（UHC）和国内生产总值（GDP）呈负相关，这表明随着经济发展和各国医疗保健系统绩效的改善，压疮的ASR有所下降。
