Department of Orthopaedic Surgery, Inha University Hospital, Incheon, Republic of Korea.
J Int Med Res. 2022 Apr;50(4):3000605221085062. doi: 10.1177/03000605221085062.
To compare the clinical outcomes among three analgesic techniques, continuous femoral nerve block (CFNB), epidural patient-controlled analgesia (EPCA) and periarticular injection (PAI), in patients undergoing total knee arthroplasty (TKA).
This retrospective case-control study enrolled patients that underwent TKA. Visual analogue scale (VAS) pain scores, sleep disturbance, additional opioid consumption and incidence of opioid-related side-effects were assessed.
A total of 120 patients were categorized into three groups: EPCA (group A, = 40), PAI (group B, = 40) and CFNB (group C, = 40). Group C had significantly lower VAS pain scores than groups A and B at 8, 12 and 24 h after TKA. There were no significant differences in VAS pain scores among the three groups from 48 h after TKA. Sleep quality on the first day after surgery was significantly better in group C than in groups A and B. Additional opioid consumption was significantly lower in the group C than in the groups A and B. Group C showed a lower rate of opioid-related side-effects than groups A and B.
CFNB was a more effective additional analgesic technique than EPCA or PAI for acute postoperative pain control within 24 h of TKA.
比较三种镇痛技术(连续股神经阻滞(CFNB)、硬膜外患者自控镇痛(EPCA)和关节周围注射(PAI))在全膝关节置换术(TKA)患者中的临床效果。
本回顾性病例对照研究纳入了接受 TKA 的患者。评估了视觉模拟评分(VAS)疼痛评分、睡眠障碍、额外阿片类药物消耗和阿片类药物相关副作用的发生率。
共纳入 120 例患者,分为三组:EPCA(A 组,n=40)、PAI(B 组,n=40)和 CFNB(C 组,n=40)。在 TKA 后 8、12 和 24 小时,C 组的 VAS 疼痛评分明显低于 A 组和 B 组。在 TKA 后 48 小时,三组之间的 VAS 疼痛评分无显著差异。手术后第一天,C 组的睡眠质量明显优于 A 组和 B 组。C 组的额外阿片类药物消耗明显低于 A 组和 B 组。C 组的阿片类药物相关副作用发生率低于 A 组和 B 组。
与 EPCA 或 PAI 相比,CFNB 是一种更有效的术后辅助镇痛技术,可在 TKA 后 24 小时内控制急性术后疼痛。