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一项关于在全膝关节置换术(TKA)后使用0.2%罗哌卡因进行连续股神经阻滞(CFNB)和连续硬膜外输注(CEI)以进行术后镇痛和膝关节康复的随机对照试验。

A randomized, controlled trial of comparison of a continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) using 0.2% ropivacaine for postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA).

作者信息

Gandhi Harshil J, Trivedi Lopa H, Tripathi Deepshikha C, Dash Deepika M, Khare Amit M, Gupta Mayur U

机构信息

Department of Anaesthesiology, Government Medical College and Sir T. Hospital, Bhavnagar, Gujarat, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2019 Jul-Sep;35(3):386-389. doi: 10.4103/joacp.JOACP_134_16.

Abstract

BACKGROUND AND AIMS

Postoperative pain relief following total knee arthroplasty (TKA) is a major concern as it will help to achieve an effective functional outcome. The present study was conducted to compare continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) techniques using ropivacaine.

MATERIAL AND METHODS

Forty patients were randomly allocated into group F and group E to receive 0.2% ropivacaine through femoral catheter or epidural catheter respectively. An infusion was started @6 ml/h post-operatively when VAS was ≥4. The dose was titrated to keep VAS <4 (with minimum rate 2 ml/h and maximum rate 10 ml/h). If VAS ≥4 occurred despite maximum rate of infusion, a rescue analgesic was given. Primary objectives were to compare visual analogue score (VAS), rehabilitation indices, and rescue analgesic requirement. Secondary objectives were to assess patient and surgeon's satisfaction score, motor blockade, and complications if any.

RESULTS

The mean VAS score, rehabilitation goals, rescue analgesic requirement, and patient's and surgeon's mean satisfaction scores were comparable in both the groups. Motor blockade was not seen and though the number of side effects were more in group E, they did not achieve statistical or clinical significance.

CONCLUSION

CFNB can be used as an alternative, effective postoperative analgesic technique for TKA.

摘要

背景与目的

全膝关节置换术(TKA)后的术后疼痛缓解是一个主要问题,因为它有助于实现有效的功能结果。本研究旨在比较使用罗哌卡因的连续股神经阻滞(CFNB)和连续硬膜外输注(CEI)技术。

材料与方法

40例患者被随机分为F组和E组,分别通过股动脉导管或硬膜外导管接受0.2%罗哌卡因。术后当视觉模拟评分(VAS)≥4时,以6 ml/h的速度开始输注。剂量进行滴定以保持VAS<4(最低速度2 ml/h,最高速度10 ml/h)。如果尽管以最大输注速度仍出现VAS≥4,则给予解救镇痛药。主要目的是比较视觉模拟评分(VAS)、康复指标和解救镇痛药需求。次要目的是评估患者和外科医生的满意度评分、运动阻滞以及是否有并发症。

结果

两组的平均VAS评分、康复目标、解救镇痛药需求以及患者和外科医生的平均满意度评分相当。未观察到运动阻滞,尽管E组的副作用数量更多,但未达到统计学或临床意义。

结论

CFNB可作为TKA术后一种替代的、有效的镇痛技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ea/6748000/b382cc003b7b/JOACP-35-386-g001.jpg

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