Hooshang Hamed, Farahani Ali Vasheghani, Rezaeizadeh Hossein, Forouzannia Seyed Khalil, Alaeddini Farshid, Ashraf Haleh, Karimi Mehrdad
Department of Persian Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Clinical Cardiac Electrophysiology, Department of Cardiology, School of Medicine, Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran Heart Center, University of Medical Sciences, Tehran, Iran.
Evid Based Complement Alternat Med. 2022 Mar 28;2022:5032681. doi: 10.1155/2022/5032681. eCollection 2022.
Bypass graft surgery of the coronary artery has a significant effect on the creation and development of sexual dysfunction among male patients. The previous studies have demonstrated that date palm pollen (DPP) increases the count and quality of sperm. Additionally, it has been shown that DPP has a protective effect against myocardial infarction and cardiac remodeling. Therefore, this is the first study investigating the impact of DPP () on managing male sexual dysfunction after coronary artery bypass graft.
This randomized, double-blind, placebo-controlled clinical trial was conducted on 60 patients (DPP group = 30, control group = 30) of Iranian men after coronary artery bypass graft. Two parallel groups were randomly generated from the study participants. The intervention group was prescribed 3 grams of the powder of DPP twice a day (9 AM and 9 PM) for two months, while the control group received the same prescription of the placebo powder.
The DPP consumption significantly increased the International Index of Erectile Function (IIEF) (from 23.21 to 46.57) and the Hurlbert Index of Sexual Desire (HISD) (from 59.39 to 64.45) scores over time in the intervention group. However, there were no significant changes in the control group.
Daily intake of 6 g DPP for two months exhibited beneficial effects on the symptoms of male sexual dysfunction in patients who have undergone coronary artery bypass graft (CABG).
冠状动脉搭桥手术对男性患者性功能的产生和发展有显著影响。先前的研究表明，海枣花粉（DPP）可增加精子数量并提高精子质量。此外，研究表明DPP对心肌梗死和心脏重塑具有保护作用。因此，这是第一项研究DPP对冠状动脉搭桥术后男性性功能障碍治疗影响的研究。
这项随机、双盲、安慰剂对照的临床试验针对60名伊朗男性冠状动脉搭桥术后患者进行（DPP组 = 30，对照组 = 30）。从研究参与者中随机产生两个平行组。干预组患者每天两次（上午9点和晚上9点）服用3克DPP粉末，持续两个月，而对照组则服用相同配方的安慰剂粉末。
随着时间的推移，干预组中DPP的摄入显著提高了国际勃起功能指数（IIEF）（从23.21提高到46.57）和赫尔伯特性欲指数（HISD）（从59.39提高到64.45）得分。然而，对照组没有显著变化。
冠状动脉搭桥术（CABG）患者连续两个月每天摄入6克DPP对男性性功能障碍症状有有益影响。
