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患有X连锁和“常见变异型”低丙种球蛋白血症患者的B细胞

B cells in patients with X-linked and 'common variable' hypogammaglobulinaemia.

作者信息

Golay J T, Webster A D

出版信息

Clin Exp Immunol. 1986 Jul;65(1):100-4.

PMID:3539422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1542263/
Abstract

E- cells from three patients with X-linked and three patients with non-familial 'common variable' hypogammaglobulinaemia were stained by indirect immunofluorescence with a panel of B cell specific monoclonal antibodies (anti-Bp95, Bp35 and Bp135). The number of B cells detected with the pan-B cell antibodies was variable between patients. One patient in each group was found to have near normal numbers of circulating B cells although those of the X-linked patient were clearly immature.

摘要

来自3名X连锁型和3名非家族性“常见变异型”低丙种球蛋白血症患者的E细胞，用一组B细胞特异性单克隆抗体（抗Bp95、Bp35和Bp135）进行间接免疫荧光染色。用泛B细胞抗体检测到的B细胞数量在患者之间存在差异。每组中有一名患者的循环B细胞数量接近正常，尽管X连锁型患者的B细胞明显不成熟。

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Clin Exp Immunol. 1986 Jul;65(1):100-4.
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本文引用的文献

1
Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases.来自原发性免疫缺陷疾病患者的爱泼斯坦-巴尔病毒诱导的淋巴母细胞系。
Scand J Immunol. 1980;11(2):155-62. doi: 10.1111/j.1365-3083.1980.tb00221.x.
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Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody.通过E玫瑰花结形成或单克隆抗T细胞抗体所界定的人“T”淋巴细胞的独特功能特性。
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B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes.B4，一种在正常、有丝分裂原激活的及恶性B淋巴细胞上表达的人类B淋巴细胞相关抗原。
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Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.对人类单核细胞、粒细胞和内皮细胞具有特异性的单克隆抗体。
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5
Epstein-Barr virus-induced lymphoblastoid cell lines derived from the peripheral blood of patients with X-linked agammaglobulinemia can secrete IgM.源自X连锁无丙种球蛋白血症患者外周血的爱泼斯坦-巴尔病毒诱导的淋巴母细胞系可分泌IgM。
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6
Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia.来自X连锁无丙种球蛋白血症患者的前B细胞和其他可能的前体淋巴细胞系。
J Exp Med. 1980 Dec 1;152(6):1519-26. doi: 10.1084/jem.152.6.1519.
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Characterization of a human B lymphocyte-specific antigen.一种人类B淋巴细胞特异性抗原的特性描述。
J Immunol. 1980 Oct;125(4):1678-85.
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Surface-bound immunoglobulin on lymphocytes from normal and immunodeficient humans.来自正常人和免疫缺陷患者淋巴细胞表面结合的免疫球蛋白。
Scand J Immunol. 1972;1(1):1-12. doi: 10.1111/j.1365-3083.1972.tb03730.x.
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Immunoglobulins on the surface of lymphocytes in fifty patients with primary immunodeficiency diseases.五十例原发性免疫缺陷病患者淋巴细胞表面的免疫球蛋白
Clin Immunol Immunopathol. 1973 Jan;1(2):241-56. doi: 10.1016/0090-1229(73)90025-1.
10
B cells in patients with X-linked agammaglobulinemia.X连锁无丙种球蛋白血症患者的B细胞。
J Immunol. 1985 May;134(5):3070-4.