患有X连锁和“常见变异型”低丙种球蛋白血症患者的B细胞
B cells in patients with X-linked and 'common variable' hypogammaglobulinaemia.
作者信息
Golay J T, Webster A D
出版信息
Clin Exp Immunol. 1986 Jul;65(1):100-4.
Abstract
E- cells from three patients with X-linked and three patients with non-familial 'common variable' hypogammaglobulinaemia were stained by indirect immunofluorescence with a panel of B cell specific monoclonal antibodies (anti-Bp95, Bp35 and Bp135). The number of B cells detected with the pan-B cell antibodies was variable between patients. One patient in each group was found to have near normal numbers of circulating B cells although those of the X-linked patient were clearly immature.
摘要
来自3名X连锁型和3名非家族性“常见变异型”低丙种球蛋白血症患者的E细胞，用一组B细胞特异性单克隆抗体（抗Bp95、Bp35和Bp135）进行间接免疫荧光染色。用泛B细胞抗体检测到的B细胞数量在患者之间存在差异。每组中有一名患者的循环B细胞数量接近正常，尽管X连锁型患者的B细胞明显不成熟。
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