WC102, Department of Family Consumer Science, Minnesota State University, Mankato, Mankato, MN, 56001, USA.
Department of Recreation, Parks & Leisure Services, Minnesota State University, Mankato, Mankato, MN, USA.
Int J Obes (Lond). 2022 Jul;46(7):1328-1331. doi: 10.1038/s41366-022-01118-y. Epub 2022 Apr 9.
BACKGROUND/GOAL: Caloric restriction-the most prevalent obesity treatment-has a 97% failure rate when spread over 5-7 years. Sarcopenic obesity is thought to be the consequence of chronic dieting and the cause of weight management problems. This pilot study's goal was to develop a screening questionnaire that detects sarcopenic obesity in young and middle-aged female adults.
SUBJECTS/METHOD: A total of 23 women (ages 19-59) completed a sarcopenic obesity questionnaire and were assessed for total body weight (TBWt), percent fat mass, and percent fat-free mass (%FFM) using the Bod Pod (air plethsmography), and bioelectrical impedance analysis (BIA). Appendicular skeletal mass (ASM) was calculated using BIA. Resting energy expenditure was determined using indirect calorimetry, and the basal metabolic rate (BMR) was calculated using BIA.
The screening questionnaire score was negatively correlated with BMR (r = 0.885), %FFM (r = 0.86), ASM (r = 0.79) relative to TBWt and to ASM/BMI (r = 0.58). The screening questionnaire had an acceptable sensitivity (83%) and specificity (87%) in detecting sarcopenia measured using ASM/BMI.
This pilot intimates that subjects who frequently dieted suffered from a disproportionally lower FFM and BMR relative to the TBWt. The questionnaire can help clinicians recognize the presence of sarcopenic obesity in patients.
背景/目标：热量限制——最常见的肥胖治疗方法——在 5-7 年内的成功率为 97%。人们认为肌少症性肥胖是慢性节食的结果，也是体重管理问题的原因。这项初步研究的目的是开发一种筛查问卷，以检测年轻和中年女性成年人的肌少症性肥胖。
受试者/方法：共有 23 名女性（年龄 19-59 岁）完成了肌少症性肥胖问卷，并使用人体测体仪（空气 plethsmography）评估了总体重（TBWt）、体脂肪百分比和体脂肪无脂百分比（%FFM），以及生物电阻抗分析（BIA）。使用 BIA 计算四肢骨骼肌质量（ASM）。通过间接热量测定法确定静息能量消耗，通过 BIA 计算基础代谢率（BMR）。
筛查问卷评分与 BMR（r=0.885）、%FFM（r=0.86）、ASM（r=0.79）呈负相关，相对于 TBWt 和 ASM/BMI，以及与 ASM/BMI（r=0.58）呈负相关。筛查问卷在检测使用 ASM/BMI 测量的肌少症方面具有可接受的灵敏度（83%）和特异性（87%）。
这项初步研究表明，经常节食的受试者的 FFM 和 BMR 相对于 TBWt 不成比例地降低。该问卷可以帮助临床医生识别患者中存在的肌少症性肥胖。
