Ramaswamy Anuradha
Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA.
Division of Pulmonary, Critical Care, Care New England Kent Hospital, Warwick, RI USA.
Curr Pulmonol Rep. 2022;11(1):15-28. doi: 10.1007/s13665-021-00283-1. Epub 2022 Apr 2.
Lung cancer screening with low-dose CT (LDCT) scans has been widely accepted within the last decade. Our knowledge and ability to implement screening has greatly increased because of significant research efforts and guidelines from multiple professional societies. The purpose of this review is to summarize some of the significant findings pertaining to lung cancer screening.
Screening with LDCT decreases lung cancer mortality in multiple studies. Use of validated risk prediction calculators can improve patient selection and screening efficiency. Shared decision making and smoking cessation counseling are essential screening components. Multidisciplinary involvement is required for the success of a screening program.
Lung cancer screening is complex, and implementation of a successful program requires multidisciplinary expertise. Further prospective studies are required to determine optimal patient selection, screening intervals, and strategies to maximize benefit while further decreasing harms.'
在过去十年中，低剂量CT（LDCT）扫描用于肺癌筛查已被广泛接受。由于多个专业协会的大量研究工作和指南，我们实施筛查的知识和能力有了很大提高。本综述的目的是总结一些与肺癌筛查相关的重要发现。
多项研究表明，LDCT筛查可降低肺癌死亡率。使用经过验证的风险预测计算器可以改善患者选择和筛查效率。共同决策和戒烟咨询是筛查的重要组成部分。筛查计划的成功需要多学科参与。
肺癌筛查很复杂，成功实施一个筛查计划需要多学科专业知识。需要进一步的前瞻性研究来确定最佳的患者选择、筛查间隔以及在进一步降低危害的同时使获益最大化的策略。
