Hu Shasha, Cheng Shaowen, Wu Yu, Wang Yanyan, Li XinNian, Zheng Jiaxuan, Li Jiao, Peng Lei, Yang Jian
Department of Pathology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Trauma Center, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Front Surg. 2022 Mar 24;9:861739. doi: 10.3389/fsurg.2022.861739. eCollection 2022.
Giant cell tumor (GCT) of the bone is a rare benign, locally aggressive tumor that occurs in the epiphysis of long bones, especially the lower femur and the upper tibia. GCT of the bone of cranial origin is very rare, accounting for 1% of all GCT of the bone. We report the diagnosis, treatment, and immunohistochemistry of a rare case of intracranial GCT of the bone. We also review and summarize the imaging features, diagnostic markers, and current major treatment options for GCT of the bone. Our case and literature review emphasizes the importance of considering the full picture when making a diagnosis, rather than relying on imaging alone to make the diagnosis.
骨巨细胞瘤（GCT）是一种罕见的良性、局部侵袭性肿瘤，发生于长骨的骨骺，尤其是股骨下端和胫骨上端。颅骨起源的骨巨细胞瘤非常罕见，占所有骨巨细胞瘤的1%。我们报告一例罕见的颅内骨巨细胞瘤的诊断、治疗及免疫组化情况。我们还回顾并总结了骨巨细胞瘤的影像学特征、诊断标志物及当前主要治疗方案。我们的病例及文献回顾强调了诊断时全面考虑的重要性，而非仅依靠影像学进行诊断。
