Wang Ting, Pei Yinghua, Qiu Xiaojian, Wang Juan, Wang Yuling, Zhang Jie
Department of Respiratory and Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ear Nose Throat J. 2025 Jan;104(1):47-53. doi: 10.1177/01455613221094441. Epub 2022 Apr 11.
Superimposed high-frequency jet ventilation (SHFJV) is a new type of jet ventilation that simultaneously uses high- and low-frequency types of jet ventilation. We compared SHFJV with the conventional high-frequency jet ventilation (CHFJV) in interventional bronchoscopy in terms of safety and effectiveness. : A multi-centre prospective random single-blind clinical trial was conducted by three interventional bronchoscopy centres. Patients who underwent diagnostic or therapeutic bronchoscopy under general anaesthesia were admitted and divided into two groups: SHFJV group (trial group) and CHFJV group (control group). PaO2 and PaCO2 were recorded before anaesthesia and during and after the procedure. SpO2 and etCO2 were recorded every 10 min throughout the procedure. Patients were observed until 24 h post-bronchoscopy. Sixty patients were included in the study. Twenty-nine were in the trial group, and 31 were in the control group. Both groups had no significant differences in demographic data. In the control group, the PaO2 measured in the operation was higher than that in the trial group (p = 0.023). The values of etCO2 in the control group were more dispersed than those of the trial group. When the procedure time was over 90 minutes, the etCO2 in the control group significantly increased (p = 0.01), while the etCO2 in trial group remained stable (p = 0.594). There were more patients with PaCO2 ≥ 50 mmHg during the procedure in the control group than in the trial group (p = 0.042). : SHFJV is effective and safe in interventional bronchoscopy. It may provide more effective and stabilised ventilation than CHFJV in cases with long procedure times.
叠加高频喷射通气（SHFJV）是一种新型的喷射通气方式，它同时采用高频和低频喷射通气。我们在介入性支气管镜检查中，就安全性和有效性方面，将SHFJV与传统高频喷射通气（CHFJV）进行了比较。：由三个介入性支气管镜检查中心开展了一项多中心前瞻性随机单盲临床试验。纳入在全身麻醉下接受诊断性或治疗性支气管镜检查的患者，并将其分为两组：SHFJV组（试验组）和CHFJV组（对照组）。记录麻醉前、手术期间及术后的动脉血氧分压（PaO2）和动脉血二氧化碳分压（PaCO2）。在整个手术过程中，每隔10分钟记录脉搏血氧饱和度（SpO2）和呼气末二氧化碳分压（etCO2）。观察患者直至支气管镜检查后24小时。该研究共纳入60例患者。试验组29例，对照组31例。两组在人口统计学数据方面无显著差异。对照组术中测得的PaO2高于试验组（p = 0.023）。对照组的etCO2值比试验组更分散。当手术时间超过90分钟时，对照组的etCO2显著升高（p = 0.01），而试验组的etCO2保持稳定（p = 0.594）。对照组术中动脉血二氧化碳分压≥50 mmHg的患者比试验组更多（p = 0.042）。：SHFJV在介入性支气管镜检查中是有效且安全的。在手术时间较长的情况下，它可能比CHFJV提供更有效和稳定的通气。
