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癌症耐药的分子机制:新兴生物标志物及克服肿瘤进展的潜在靶点

Molecular Mechanisms of Cancer Drug Resistance: Emerging Biomarkers and Promising Targets to Overcome Tumor Progression.

作者信息

Fontana Fabrizio, Anselmi Martina, Limonta Patrizia

机构信息

Department of Pharmacological and Biomolecular Sciences, University of Milano, 20133 Milano, Italy.

出版信息

Cancers (Basel). 2022 Mar 23;14(7):1614. doi: 10.3390/cancers14071614.

DOI:10.3390/cancers14071614
PMID:35406386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8997078/
Abstract

Cancer still represents a major global burden, being the second leading cause of death worldwide [...].

摘要

癌症仍然是一个重大的全球负担,是全球第二大死因[……]。

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本文引用的文献

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Systemic Mobilization of Breast Cancer Resistance Protein in Response to Oncogenic Stress.响应致癌应激时乳腺癌耐药蛋白的全身动员
Cancers (Basel). 2022 Jan 9;14(2):313. doi: 10.3390/cancers14020313.
2
Cancer statistics, 2022.癌症统计数据,2022 年。
CA Cancer J Clin. 2022 Jan;72(1):7-33. doi: 10.3322/caac.21708. Epub 2022 Jan 12.
3
The determinants of very severe immune-related adverse events associated with immune checkpoint inhibitors: A prospective study of the French REISAMIC registry.与免疫检查点抑制剂相关的极重度免疫相关不良事件的决定因素:法国 REISAMIC 注册前瞻性研究。
Eur J Cancer. 2021 Nov;158:217-224. doi: 10.1016/j.ejca.2021.08.048. Epub 2021 Oct 7.
4
Microbiome in drug resistance to colon cancer.微生物群与结肠癌耐药性
Curr Opin Physiol. 2021 Oct;23. doi: 10.1016/j.cophys.2021.100472. Epub 2021 Aug 17.
5
Breast Cancer Drug Resistance: Overcoming the Challenge by Capitalizing on MicroRNA and Tumor Microenvironment Interplay.乳腺癌耐药性:通过利用微小RNA与肿瘤微环境的相互作用来克服这一挑战
Cancers (Basel). 2021 Jul 22;13(15):3691. doi: 10.3390/cancers13153691.
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Drug Resistance in Osteosarcoma: Emerging Biomarkers, Therapeutic Targets and Treatment Strategies.骨肉瘤中的耐药性:新兴生物标志物、治疗靶点与治疗策略
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