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从传统储存的母羊奶奶酪中分离出的产细菌素菌株LP17L/1及其有益潜力。

Bacteriocin-Producing Strain LP17L/1 Isolated from Traditional Stored Ewe's Milk Cheese and Its Beneficial Potential.

作者信息

Lauková Andrea, Tomáška Martin, Fraqueza Maria Joao, Szabóová Renáta, Bino Eva, Ščerbová Jana, Pogány Simonová Monika, Dvorožňáková Emília

机构信息

Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Šoltésovej 4-6, 040 01 Košice, Slovakia.

Dairy Research Institute, a.s., Dlhá 95, 010 01 Žilina, Slovakia.

出版信息

Foods. 2022 Mar 25;11(7):959. doi: 10.3390/foods11070959.

Abstract

Stored ewe's milk lump cheese is a local product that can be a source of autochthonous beneficial microbiota, especially lactic acid bacteria. The aim of this study was to show the antimicrobial potential of LP17L/1 isolated from stored ewe's milk lump cheese. LP17L/1 is a non-hemolytic, non-biofilm-forming strain, susceptible to antibiotics. It contains genes for 10 bacteriocins-plantaricins and exerted active bacteriocin with in vitro anti-staphylococcal and anti-listerial effect. It does not produce damaging enzymes, but it produces β-galactosidase. It also sufficiently survives in Balb/c mice without side effects which indicate its safety. Moreover, a reduction in coliforms in mice jejunum was noted. LP17L/1 is supposed to be a promising additive for Slovak local dairy products.

摘要

储存的母羊奶块状奶酪是一种当地产品,可能是本地有益微生物群的来源,尤其是乳酸菌。本研究的目的是展示从储存的母羊奶块状奶酪中分离出的LP17L/1的抗菌潜力。LP17L/1是一种不溶血、不形成生物膜的菌株,对抗生素敏感。它含有10种细菌素——植物乳杆菌素的基因,并产生具有体外抗葡萄球菌和抗李斯特菌作用的活性细菌素。它不产生破坏性酶,但产生β-半乳糖苷酶。它在Balb/c小鼠中也能充分存活且无副作用,这表明了它的安全性。此外,还注意到小鼠空肠中的大肠菌群有所减少。LP17L/1有望成为斯洛伐克当地乳制品的一种有前景的添加剂。

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