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使用连续血糖监测仪测定以大米为主的混合餐的血糖生成指数、其对24小时血糖曲线的影响及其对超重和肥胖青年成人膳食偏好的影响。

Use of a Continuous Glucose Monitor to Determine the Glycaemic Index of Rice-Based Mixed Meals, Their Effect on a 24 h Glucose Profile and Its Influence on Overweight and Obese Young Adults' Meal Preferences.

作者信息

Chekima Khadidja, Wong Benjamin Tziak Ze, Noor Mohd Ismail, Ooi Yasmin Beng Houi, Yan See Wan, Chekima Brahim

机构信息

Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya 47500, Selangor, Malaysia.

Faculty of Social Sciences & Leisure Management, Taylor's University, Subang Jaya 47500, Selangor, Malaysia.

出版信息

Foods. 2022 Mar 28;11(7):983. doi: 10.3390/foods11070983.

Abstract

Postprandial hyperglycaemia is associated with an increased risk of type-2 diabetes. This study aims to determine the glycaemic index (GI) of three varieties of rice-based mixed meals and their effects on glycaemic variability (GV), 24 h mean glucose levels and target ranges, and rice variety preferences among overweight and obese young adults using real-time continuous glucose monitoring (rtCGM). In a randomised controlled crossover design, 14 participants (22.8 ± 4.6 years, 32.9 ± 5.8 kg/m2) were randomly assigned to receive 3 rice-based mixed meals containing 50 g of available carbohydrates (white rice meal = WRM; brown rice meal = BRM; and parboiled basmati rice meal = PBRM) and 50 g of a glucose reference drink on alternate days. GI, GV, 24 h mean glucose levels and target ranges were measured. Rice variety preferences were compared with those of baseline data and determined at the end of the study period. Results: The analysis found that PBRM was low in GI (45.35 ± 2.06), BRM medium in GI (56.44 ± 2.34), and WRM high in GI (83.03 ± 2.19). PBRM had a significantly (p < 0.05) lower 24 h mean glucose level, higher in-target 24 h glucose level percentage and non-significantly (p > 0.05) lower GV compared to WRM. Prior to observing their postprandial glucose levels generated by rtCGM, the participants preferred WRM (64.3%) over other meals, whereas this preference changed significantly (p < 0.05) at the endpoint (PBRM, 71.4%). PBRM reduced 24 h glucose level and GV of overweight and obese young adults. The rtCGM is proven to be reliable in measuring GI, while providing robust continuous glycaemic information. This may serve as an educational tool that motivates eating behaviour changes among overweight and obese young adults.

摘要

餐后高血糖与2型糖尿病风险增加相关。本研究旨在使用实时连续血糖监测(rtCGM)来确定三种以大米为主的混合餐的血糖生成指数(GI)及其对血糖变异性(GV)、24小时平均血糖水平和目标范围的影响,以及超重和肥胖的年轻成年人对大米品种的偏好。在一项随机对照交叉设计中,14名参与者(22.8±4.6岁,32.9±5.8kg/m²)被随机分配,隔天接受3种含50克可利用碳水化合物的以大米为主的混合餐(白米饭餐=WRM;糙米饭餐=BRM;半熟印度香米饭餐=PBRM)和50克葡萄糖参考饮料。测量了GI、GV、24小时平均血糖水平和目标范围。将大米品种偏好与基线数据进行比较,并在研究期结束时确定。结果:分析发现PBRM的GI较低(45.35±2.06),BRM的GI中等(56.44±2.34),WRM的GI较高(83.03±2.19)。与WRM相比,PBRM的24小时平均血糖水平显著较低(p<0.05),24小时血糖水平处于目标范围内的百分比更高,GV无显著降低(p>0.05)。在通过rtCGM观察其餐后血糖水平之前,参与者更喜欢WRM(64.3%)而非其他餐食,而在研究终点时这种偏好发生了显著变化(p<0.05)(PBRM为71.4%)。PBRM降低了超重和肥胖年轻成年人的24小时血糖水平和GV。rtCGM被证明在测量GI方面可靠,同时能提供可靠的连续血糖信息。这可作为一种教育工具,促使超重和肥胖的年轻成年人改变饮食行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8540/8997962/45626e36c228/foods-11-00983-g001.jpg

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