Department of Biology, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Manado 95115, North Sulawesi, Indonesia.
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Kopelma Darussalam, Banda Aceh 23111, Aceh, Indonesia.
Molecules. 2022 Mar 29;27(7):2221. doi: 10.3390/molecules27072221.
The coronavirus disease 2019 (COVID-19) pandemic is still ongoing, with no signs of abatement in sight. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of this pandemic and has claimed over 5 million lives, is still mutating, resulting in numerous variants. One of the newest variants is Omicron, which shows an increase in its transmissibility, but also reportedly reduces hospitalization rates and shows milder symptoms, such as in those who have been vaccinated. As a result, many believe that Omicron provides a natural vaccination, which is the first step toward ending the COVID-19 pandemic. Based on published research and scientific evidence, we review and discuss how the end of this pandemic is predicted to occur as a result of Omicron variants being surpassed in the community. In light of the findings of our research, we believe that it is most likely true that the Omicron variant is a natural way of vaccinating the masses and slowing the spread of this deadly pandemic. While the mutation that causes the Omicron variant is encouraging, subsequent mutations do not guarantee that the disease it causes will be less severe. As the virus continues to evolve, humans must constantly adapt by increasing their immunity through vaccination.
2019 年冠状病毒病（COVID-19）大流行仍在继续，没有减弱的迹象。严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2）是导致这一大流行病的病原体，已导致超过 500 万人死亡，它仍在不断变异，产生了许多变体。最新的变体之一是奥密克戎，它的传染性增加了，但据报道住院率降低，症状也较轻，例如在已接种疫苗的人群中。因此，许多人认为奥密克戎提供了一种自然疫苗，这是结束 COVID-19 大流行的第一步。基于已发表的研究和科学证据，我们回顾和讨论了奥密克戎变体在社区中被超越如何导致预测大流行结束。鉴于我们研究的结果，我们相信奥密克戎变体很可能是一种为大众接种疫苗和减缓这种致命大流行病传播的自然方式。虽然导致奥密克戎变体的突变令人鼓舞，但随后的突变并不能保证它引起的疾病会不那么严重。随着病毒的不断进化，人类必须通过接种疫苗来不断增强免疫力，从而适应变化。
