Cheng Acga, Harikrishna Jennifer Ann, Redwood Charles S, Lit Lei Cheng, Nath Swapan K, Chua Kek Heng
Institute of Biological Science, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Centre for Research in Biotechnology for Agriculture, University of Malaya, Kuala Lumpur 50603, Malaysia.
Int J Mol Sci. 2022 Apr 2;23(7):3976. doi: 10.3390/ijms23073976.
The understanding of how genetic information may be inherited through generations was established by Gregor Mendel in the 1860s when he developed the fundamental principles of inheritance. The science of genetics, however, began to flourish only during the mid-1940s when DNA was identified as the carrier of genetic information. The world has since then witnessed rapid development of genetic technologies, with the latest being genome-editing tools, which have revolutionized fields from medicine to agriculture. This review walks through the historical timeline of genetics research and deliberates how this discipline might furnish a sustainable future for humanity.
对遗传信息如何代代相传的理解是由格雷戈尔·孟德尔在19世纪60年代确立的,当时他提出了遗传的基本原理。然而,遗传学这门科学直到20世纪40年代中期才开始蓬勃发展,当时DNA被确认为遗传信息的载体。从那时起,世界见证了遗传技术的迅速发展,最新的是基因组编辑工具,它彻底改变了从医学到农业等各个领域。这篇综述梳理了遗传学研究的历史脉络,并探讨了这一学科如何为人类提供一个可持续的未来。