Wei Qian, Guo Jin-Sheng
Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
World J Clin Cases. 2022 Mar 16;10(8):2369-2381. doi: 10.12998/wjcc.v10.i8.2369.
In recent years, marine-derived bioactive compounds have gained increasing attention because of their higher biodiversity land-derived compounds. A number of marine-derived compounds are proven to improve lipid metabolism, modulate the gut microbiota, and possess anti-inflammatory, antioxidant, antibacterial, antiviral, and antitumor activities. With the increasing understanding of the molecular landscape underlying the pathogenesis of chronic liver diseases, interest has spiked in developing new therapeutic drugs and medicine food homology from marine sources for the prevention and treatment of liver diseases.
近年来，海洋来源的生物活性化合物因其比陆地来源的化合物具有更高的生物多样性而受到越来越多的关注。许多海洋来源的化合物已被证明可改善脂质代谢、调节肠道微生物群，并具有抗炎、抗氧化、抗菌、抗病毒和抗肿瘤活性。随着对慢性肝病发病机制背后分子格局的认识不断加深，人们对开发来自海洋来源的新型治疗药物和药食同源物质以预防和治疗肝病的兴趣激增。
