Zhou Yi-Ting, Wang Ruo-Yu, Zhang Yao, Li Dong-Yi, Yu Jian
Hyperthermia Center, The Affiliated Zhongshan Hospital of Dalian University, Dalian 110006, China.
Department of Medical Oncology, The Affiliated Zhongshan Hospital of Dalian University, Dalian 110006, China.
World J Clin Cases. 2022 Mar 26;10(9):2916-2922. doi: 10.12998/wjcc.v10.i9.2916.
is a type of soft tissue sarcoma, the histologic origin and differentiation direction of which are still unclear. There are few treatment options for other than surgery. Herein we describe a patient who had multiple recurrences of postoperatively, but R0 resection was achieved by local hyperthermia combined with chemotherapy, thus providing a new treatment approach for similar situations.
A 65-year-old man sought evaluation from a physician for a mass on his right back. After surgery, the pathologic diagnosis was fibrosarcoma. During the follow-up evaluations until 2021, the patient had four relapses of varying degrees. Postoperative pathology confirmed the recurrence of on the right back. In March 2021, he underwent local hyperthermia combined with two cycles of chemotherapy for recurring lesions. After magnetic resonance imaging re-examination and preoperative examination, the patient chose surgery again. During the operation, the tumors were easy to excise, the amount of bleeding decreased significantly, and the pathologic evaluation confirmed that one of the specimens was an R0 excision.
Local hyperthermia combined with chemotherapy enables R0 resection to be achieved in patients with advanced recurrence.
是一种软组织肉瘤,其组织学起源和分化方向仍不清楚。除手术外,治疗选择很少。在此我们描述一名患者,其术后多次复发,但通过局部热疗联合化疗实现了R0切除,从而为类似情况提供了一种新的治疗方法。
一名65岁男性因右背部肿块寻求医生评估。手术后,病理诊断为纤维肉瘤。在直至2021年的随访评估期间,患者出现了四次不同程度的复发。术后病理证实右背部复发。2021年3月,他因复发病灶接受了局部热疗联合两个周期的化疗。经过磁共振成像复查和术前检查后,患者再次选择手术。手术过程中,肿瘤易于切除,出血量显著减少,病理评估证实其中一个标本为R0切除。
局部热疗联合化疗能够使晚期复发患者实现R0切除。