一例在接受手术及放化疗等多种癌症治疗后发生的食管未分化多形性肉瘤。
A case of undifferentiated pleomorphic sarcoma in esophagus after multiple cancer treatments of surgery and chemoradiotherapy.
作者信息
Ebata Yuho, Sakaguchi Yoshihisa, Tsuda Yasuo, Nambara Sho, Kudou Kensuke, Kusumoto Eiji, Yoshida Rintaro, Kusumoto Tetsuya, Ikejiri Koji
机构信息
Department of Gastroenterological Surgery and Clinical Research Institute, Kyushu Medical Center, Jigyohama 1-8-1, Chuo-Ku, Fukuoka, 810-8563, Japan.
出版信息
Surg Case Rep. 2022 Nov 4;8(1):205. doi: 10.1186/s40792-022-01560-0.
BACKGROUND
Undifferentiated pleomorphic sarcoma (UPS) in the esophagus is extremely rare. Therefore, there are few reports of UPS in the esophagus (UPSE). We present a case of UPSE after multiple cancer treatments.
CASE PRESENTATION
A 73-year-old man with a history of cancer treatment, including distal gastrectomy, transverse colectomy, and chemoradiotherapy, was diagnosed with an elevated lesion such as a submucosal tumor in the lower esophagus by regular endoscopy. A boring biopsy was performed, and the specimen showed features of sarcoma. The patient underwent a partial esophagectomy without lymph node dissection. Histopathological findings confirmed an undifferentiated pleomorphic sarcoma. Adjuvant therapy was not administered, and the patient survived without recurrence 1 year after surgery.
CONCLUSIONS
Currently, complete resection is the only treatment option for UPSE. An optimal treatment strategy using chemotherapy or radiotherapy should be established.
背景
食管未分化多形性肉瘤（UPS）极为罕见。因此，关于食管未分化多形性肉瘤（UPSE）的报道很少。我们报告一例多次癌症治疗后发生的UPSE病例。
病例介绍
一名73岁男性，有癌症治疗史，包括远端胃切除术、横结肠切除术和放化疗，通过定期内镜检查诊断为食管下段有一个隆起性病变，如黏膜下肿瘤。进行了钻取活检，标本显示为肉瘤特征。患者接受了部分食管切除术，未进行淋巴结清扫。组织病理学检查结果证实为未分化多形性肉瘤。未给予辅助治疗，患者术后1年存活且无复发。
结论
目前，完整切除是UPSE的唯一治疗选择。应制定使用化疗或放疗的最佳治疗策略。
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