Gheorghe Andreea-Georgiana, Niţu Floarea Mimi, Stanciu Ilona Andreea, Streba Costin-Teodor
PhD Student, Department of Pulmonology, University of Medicine and Pharmacy of Craiova, Romania.
Department of Pulmonology, "Victor Babeș" Clinical Hospital of Infectious Disease and Pulmonology, Craiova, Romania.
Curr Health Sci J. 2021 Oct-Dec;47(4):485-493. doi: 10.12865/CHSJ.47.04.02. Epub 2021 Dec 31.
Lung cancer, one of the most prominent malignancies of today worldwide, affects mainly men; however, recently women have also been increasingly afflicted by the disease. Our aim was to retrospectively analyze a series of potential risk factors for the disease and their potential to affect both genders.
Our retrospective study relied on anonymized data collected between 2017 and 2020 at a single hospital specialized on lung diseases. After receiving ethical clearance, data pertaining to risk factors as well as statistical aspects of the lot were recorded and analyzed.
We found 493 patients (398 men) aged between 31 and 90 years (median 67) who were found with lung tumors and selected a matched cohort of patients with other diseases. We found positive associations between the presence of smoking, COPD, or pollution and the occurrence of lung cancer. Almost all lung cancer patients presented different significant associated diseases. Family history also favored the appearance of lung cancer.
Several risk factors remain high in lung tumor patients, and rapid measures to diminish the impact of such factors are needed in order to decrease the overall incidence of this pathology.
肺癌是当今全球最主要的恶性肿瘤之一，主要影响男性；然而，近年来女性患该疾病的人数也在不断增加。我们的目的是回顾性分析一系列该疾病的潜在风险因素及其对两性的影响。
我们的回顾性研究依赖于2017年至2020年期间在一家专门治疗肺部疾病的医院收集的匿名数据。在获得伦理批准后，记录并分析了与风险因素以及该批次统计方面相关的数据。
我们发现了493例年龄在31岁至90岁（中位数67岁）之间的患者（398名男性）患有肺部肿瘤，并选取了一组匹配的患有其他疾病的患者。我们发现吸烟、慢性阻塞性肺疾病（COPD）或污染与肺癌的发生之间存在正相关。几乎所有肺癌患者都患有不同的显著相关疾病。家族史也有利于肺癌的出现。
肺癌患者中几种风险因素仍然很高，需要迅速采取措施减轻这些因素的影响，以降低这种病理状况（肺癌）的总体发病率。
