Xiong Jianping, Xie Shiqi, Lu Hongshuang, Chen Changyu, Wang Yining, Wang Ziye, Kamoi Koju, Yoshida Takeshi, Yasuda Shintaro, Ohno-Matsui Kyoko
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 1138510, Japan.
Department of Advanced Ophthalmic Imaging, Tokyo Medical and Dental University, Tokyo, Japan.
Jpn J Ophthalmol. 2025 Sep 12. doi: 10.1007/s10384-025-01260-w.
To determine whether retro-mode scanning laser ophthalmoscopy (RMSLO) can detect optic disc abnormalities in highly myopic eyes.
A retrospective clinical study.
Patients with high myopia who had undergone RMSLO imaging and optic disc-centered optical coherence tomographic (OCT) examinations between July and September 2022 were studied. The existence and extent of the hyporeflective areas in the RMSLO images were determined. The OCT images were used to detect lamina cribrosa (LC) abnormalities, and the correspondence of the LC abnormalities to the location of the hyporeflective areas in the RMSLO images was determined.
Thirty-eight eyes of 21 patients with high myopia were studied. The mean age of the patients was 58.6±12.3 years, and the mean axial length was 30.54±1.96 mm. Hyporeflective areas were detected on the optic nerve head in the RMSLO images in 37 eyes (97.4%). In these 37 eyes, OCT detected defects of the LC and enlarged LC pores corresponding to the hyporeflective areas. The maximum width of the LC abnormalities in the OCT images corresponded to the extent of the hyporeflective areas in the RMSLO images.
RMSLO can obtain images with hyporeflective areas on the optic disc in highly myopic eyes that correspond to areas of LC defects observed in the OCT images. RMSLO imaging can detect the enlarged LC pores as hyporeflective abnormalities. We conclude that RMSLO is helpful in detecting abnormalities of the LC of the optic disc.
确定逆向模式扫描激光检眼镜（RMSLO）能否检测高度近视眼的视盘异常。
一项回顾性临床研究。
对2022年7月至9月间接受RMSLO成像和以视盘为中心的光学相干断层扫描（OCT）检查的高度近视患者进行研究。确定RMSLO图像中低反射区的存在和范围。利用OCT图像检测筛板（LC）异常，并确定LC异常与RMSLO图像中低反射区位置的对应关系。
对21例高度近视患者的38只眼进行了研究。患者的平均年龄为58.6±12.3岁，平均眼轴长度为30.54±1.96mm。37只眼（97.4%）的RMSLO图像在视神经乳头处检测到低反射区。在这37只眼中，OCT检测到与低反射区相对应的LC缺损和LC孔扩大。OCT图像中LC异常的最大宽度与RMSLO图像中低反射区的范围相对应。
RMSLO能够获取高度近视眼视盘上出现低反射区的图像，这些区域与OCT图像中观察到的LC缺损区域相对应。RMSLO成像能够将扩大的LC孔检测为低反射异常。我们得出结论，RMSLO有助于检测视盘LC的异常。
