Goerttler Tsepo, Kwon Eun-Hae, Fleischer Michael, Stettner Mark, Tönges Lars, Klebe Stephan
Department of Neurology, Essen University Hospital, 45147 Essen, Germany.
Department of Neurology, Ruhr University Bochum, 44801 Bochum, Germany.
Brain Sci. 2022 Mar 28;12(4):456. doi: 10.3390/brainsci12040456.
Neurological manifestations during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are of interest, regarding acute treatment and the so-called post-COVID-19 syndrome. Parkinson's disease (PD) is one of the most common neurodegenerative movement disorders worldwide. Hence, the influence of SARS-CoV-2 and the COVID-19 syndrome on PD patients has raised many questions and produced various publications with conflicting results. We reviewed the literature, with respect to symptoms, treatment, and whether the virus itself might cause PD during the SARS-CoV-2 pandemic in SARS-CoV-2-affected symptomatic PD patients (COVID-19 syndrome). In addition, we comment on the consequences in non-symptomatic and non-affected PD patients, as well as post-COVID syndrome and its potential linkage to PD, presenting our own data from our out-patient clinic.
在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行期间，神经学表现对于急性治疗以及所谓的新冠后综合征而言备受关注。帕金森病（PD）是全球最常见的神经退行性运动障碍之一。因此，SARS-CoV-2和新冠综合征对PD患者的影响引发了诸多问题，并产生了各种结果相互矛盾的出版物。我们针对受SARS-CoV-2感染且出现症状的PD患者（新冠综合征）在SARS-CoV-2大流行期间的症状、治疗以及病毒本身是否可能导致PD等方面对文献进行了综述。此外，我们对无症状和未受感染的PD患者的后果，以及新冠后综合征及其与PD的潜在联系进行了评论，并展示了我们门诊的自身数据。
