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营养与运动在骨质疏松症中的作用。

Role of nutrition and exercise in osteoporosis.

作者信息

Santora A C

出版信息

Am J Med. 1987 Jan 26;82(1B):73-9. doi: 10.1016/0002-9343(87)90275-0.

Abstract

Both adequate nutrition and exercise are essential for development of peak adult bone mass and maintenance of bone during aging. The optimal dietary level of a nutrient may vary from individual to individual and may change with age, intake of other nutrients, disease, drug therapy, or sex hormone status. Effects on spinal trabecular bone may not parallel effects on axial cortical bone. Calcium nutrition is important in the prevention of osteoporosis, as calcium is a major constituent of bone. The intake of calcium among most American adults is below the levels recommended by public health agencies. There have been no adequate prospective studies to determine the optimal intake of calcium for preservation of bone mass in young or middle-aged adults, although calcium balance studies indicate that premenopausal women require approximately 1,000 mg of calcium per day. The negative calcium balance of early menopause may be ameliorated by 1,000 mg of calcium per day; however, there is no proof that greater intakes fully reverse the effects of estrogen deficiency. Calcium requirements of both elderly men and women are likely to be greater (between 1,000 and 1,500 mg per day) due to an age-related decrease in the efficiency of intestinal calcium absorption. The optimal level of weight-bearing exercise for maintenance of bone mass in old age is probably similar to that of an active young adult. Maintenance of this activity level in middle and old age improves bone mass. An exercise prescription for elderly individuals must include an appraisal of cardiovascular and muscular-skeletal health and be designed to minimize the risk of trauma during exercise.

摘要

充足的营养和运动对于成年人达到峰值骨量以及在衰老过程中维持骨骼健康都至关重要。营养素的最佳饮食摄入量可能因人而异,并可能随年龄、其他营养素的摄入量、疾病、药物治疗或性激素状态而变化。对脊柱小梁骨的影响可能与对轴向皮质骨的影响不一致。钙营养在预防骨质疏松症中很重要,因为钙是骨骼的主要成分。大多数美国成年人的钙摄入量低于公共卫生机构推荐的水平。目前尚无足够的前瞻性研究来确定年轻或中年成年人维持骨量所需的最佳钙摄入量,尽管钙平衡研究表明,绝经前女性每天大约需要1000毫克钙。绝经早期的负钙平衡每天补充1000毫克钙可能会有所改善;然而,没有证据表明更高的摄入量能完全逆转雌激素缺乏的影响。由于肠道钙吸收效率随年龄增长而下降,老年男性和女性的钙需求量可能更大(每天1000至1500毫克)。老年时维持骨量的最佳负重运动水平可能与活跃的年轻成年人相似。在中年和老年维持这种活动水平可改善骨量。针对老年人的运动处方必须包括对心血管和肌肉骨骼健康的评估,并旨在将运动期间的受伤风险降至最低。

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