新型冠状病毒感染会引发类风湿性关节炎吗？一例病例报告。
Can SARS-CoV-2 infection trigger rheumatoid arthritis? A case report.
作者信息
Bouzid Sirine, Ben Abdelghani Kawther, Miledi Saoussen, Fazaa Alia, Laatar Ahmed
机构信息
Department of Rheumatology Mongi Slim Hospital Tunis Tunisia.
Faculty of Medicine of Tunis Tunis El Manar University Tunis Tunisia.
出版信息
Clin Case Rep. 2022 Apr 18;10(4):e05748. doi: 10.1002/ccr3.5748. eCollection 2022 Apr.
Abstract
Inflammatory arthritis has been reported after SARS-COV-2 infection. We present a case of a 38-year-old female patient who developed polyarthralgia 1 month after SARS-COV-2 infection. Musculoskeletal examination was significant for synovitis of hands and wrists. Antinuclear antibody (ANA), rheumatoid factor (RF), and anti-cyclic citrullinated peptide (CCP) antibodies were positive. Magnetic resonance imaging of the hands showed synovitis of the metacarpophalangeal joints and proximal interphalangeal joints of the hands, wrist joints, and tendinitis with tenosynovitis. The patient was diagnosed with seropositive nonerosive rheumatoid arthritis (RA) and initiated on therapy using nonsteroidal anti-inflammatory agents and disease-modifying anti-rheumatic drug methotrexate leading to an improvement in symptoms.
摘要
新型冠状病毒肺炎（SARS-CoV-2）感染后曾有炎症性关节炎的报道。我们报告一例38岁女性患者，在感染SARS-CoV-2后1个月出现多关节痛。肌肉骨骼检查显示双手和腕关节滑膜炎。抗核抗体（ANA）、类风湿因子（RF）和抗环瓜氨酸肽（CCP）抗体均呈阳性。手部磁共振成像显示掌指关节、近端指间关节、腕关节滑膜炎以及伴有腱鞘炎的肌腱炎。该患者被诊断为血清学阳性的非侵蚀性类风湿关节炎（RA），并开始使用非甾体抗炎药和改善病情抗风湿药甲氨蝶呤进行治疗，症状有所改善。
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