对患有不同严重程度和牙周炎进展风险的同卵双胞胎龈下微生物群的分析。
Analysis of subgingival microbiota in monozygotic twins with different severity and progression risk of periodontitis.
作者信息
Yamamoto Tadashi, Taniguchi Makoto, Matsunaga Kazuyuki, Kawata Yusuke, Kawamura Mari, Okubo Keisuke, Yamashiro Keisuke, Omori Kazuhiro, Takashiba Shogo
机构信息
Department of Pathophysiology - Periodontal Science Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama Japan.
Oral Microbiome Center Taniguchi Dental Clinic Takamatsu Japan.
出版信息
Clin Case Rep. 2022 Apr 18;10(4):e05725. doi: 10.1002/ccr3.5725. eCollection 2022 Apr.
The study aims to reveal the composition of subgingival bacteria in monozygotic twins with discordant in severity and progression risk of periodontitis. Microbiome analysis indicated that most bacteria were heritable but differed in their abundance and immune response. The dysbiotic bacteria can be considered as risk markers for periodontitis progression.
该研究旨在揭示牙周炎严重程度和进展风险不一致的同卵双胞胎龈下细菌的组成。微生物组分析表明，大多数细菌具有遗传性，但在丰度和免疫反应方面存在差异。失调的细菌可被视为牙周炎进展的风险标志物。
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