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对患有不同严重程度和牙周炎进展风险的同卵双胞胎龈下微生物群的分析。

Analysis of subgingival microbiota in monozygotic twins with different severity and progression risk of periodontitis.

作者信息

Yamamoto Tadashi, Taniguchi Makoto, Matsunaga Kazuyuki, Kawata Yusuke, Kawamura Mari, Okubo Keisuke, Yamashiro Keisuke, Omori Kazuhiro, Takashiba Shogo

机构信息

Department of Pathophysiology - Periodontal Science Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama Japan.

Oral Microbiome Center Taniguchi Dental Clinic Takamatsu Japan.

出版信息

Clin Case Rep. 2022 Apr 18;10(4):e05725. doi: 10.1002/ccr3.5725. eCollection 2022 Apr.

DOI:10.1002/ccr3.5725
PMID:35449775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9014707/
Abstract

The study aims to reveal the composition of subgingival bacteria in monozygotic twins with discordant in severity and progression risk of periodontitis. Microbiome analysis indicated that most bacteria were heritable but differed in their abundance and immune response. The dysbiotic bacteria can be considered as risk markers for periodontitis progression.

摘要

该研究旨在揭示牙周炎严重程度和进展风险不一致的同卵双胞胎龈下细菌的组成。微生物组分析表明，大多数细菌具有遗传性，但在丰度和免疫反应方面存在差异。失调的细菌可被视为牙周炎进展的风险标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/3128080af576/CCR3-10-e05725-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/354f0f88e03f/CCR3-10-e05725-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/e888ada8c92f/CCR3-10-e05725-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/d46e6546b1f7/CCR3-10-e05725-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/3128080af576/CCR3-10-e05725-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/354f0f88e03f/CCR3-10-e05725-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/e888ada8c92f/CCR3-10-e05725-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/d46e6546b1f7/CCR3-10-e05725-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d99/9014707/3128080af576/CCR3-10-e05725-g002.jpg

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引用本文的文献

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本文引用的文献

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Bacteriological Evaluation of Gingival Crevicular Fluid in Teeth Restored Using Fixed Dental Prostheses: An In Vivo Study.固定义齿修复后龈沟液的细菌学评价：一项体内研究。
Int J Mol Sci. 2021 May 22;22(11):5463. doi: 10.3390/ijms22115463.
2
Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis.成功治疗和持续性侵袭性牙周炎的牙周微生物组差异。
J Clin Periodontol. 2020 Aug;47(8):980-990. doi: 10.1111/jcpe.13330. Epub 2020 Jun 26.
3
Longitudinal Study of Oral Microbiome Variation in Twins.
双胞胎口腔微生物组变异的纵向研究。
Sci Rep. 2020 May 14;10(1):7954. doi: 10.1038/s41598-020-64747-1.
4
Fretibacterium sp. human oral taxon 360 is a novel biomarker for periodontitis screening in the Japanese population. fretibacterium sp. 人类口腔分类群 360 是日本人群牙周炎筛查的一种新型生物标志物。
PLoS One. 2019 Jun 19;14(6):e0218266. doi: 10.1371/journal.pone.0218266. eCollection 2019.
5
Genetic and environmental contributions to the association between mood disorder and periodontal disease: A cross-sectional study among female twins in the UK.遗传和环境因素对心境障碍与牙周病相关性的影响：英国女性双胞胎的横断面研究。
J Clin Periodontol. 2019 Jan;46(1):40-50. doi: 10.1111/jcpe.13045.
6
Subgingival microbiome of rheumatoid arthritis patients in relation to their disease status and periodontal health.类风湿关节炎患者龈下微生物组与疾病状态和牙周健康的关系。
PLoS One. 2018 Sep 19;13(9):e0202278. doi: 10.1371/journal.pone.0202278. eCollection 2018.
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Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.牙周炎：2017 年牙周病和种植体周围疾病分类世界研讨会工作组 2 的共识报告。
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