Kimmel J R, Plisetskaya E M, Pollock H G, Hamilton J W, Rouse J B, Ebner K E, Rawitch A B
Biochem Biophys Res Commun. 1986 Dec 30;141(3):1084-91. doi: 10.1016/s0006-291x(86)80154-1.
The amino acid sequence of a peptide isolated from the Pacific salmon (Oncorhynchus kisutch) endocrine pancreas has been determined. This simple 36 residue peptide is a member of the pancreatic polypeptide family. It contains a C-terminal tyrosinamide and is more homologous with porcine neuropeptide Y (NPY) (83%) and peptide YY (75%) than any of the previously characterized pancreatic polypeptides (PP). This peptide appears to be the major but not the only representative of this family of peptides present in the endocrine pancreas of this fish. This peptide is referred to as salmon pancreatic polypeptide (salmon PP).
