《健康与疾病中的 CoA》
CoA in Health and Disease.
机构信息
Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
出版信息
Int J Mol Sci. 2022 Apr 15;23(8):4371. doi: 10.3390/ijms23084371.
Abstract
Coenzyme A (CoA) and its thioester derivatives are crucial components of numerous biosynthetic and degradative pathways of the cellular metabolism (including fatty acid synthesis and oxidation, the Krebs cycle, ketogenesis, cholesterol and acetylcholine biosynthesis, amino acid degradation, and neurotransmitter biosynthesis), post-translational modifications of proteins, and the regulation of gene expression [...].
摘要
辅酶 A（CoA）及其硫酯衍生物是细胞代谢中许多生物合成和降解途径（包括脂肪酸合成和氧化、三羧酸循环、酮体生成、胆固醇和乙酰胆碱合成、氨基酸降解以及神经递质合成）、蛋白质的翻译后修饰以及基因表达调控的关键组成部分[... ]。
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