Li Zhaolong, Wang Qinghai, Liu Guangdong
Key Laboratory of Advanced Manufacturing Intelligent Technology of Ministry of Education, Harbin University of Science and Technology, Harbin 150080, China.
Harbin Vocational & Technical College, Harbin 150001, China.
Micromachines (Basel). 2022 Mar 27;13(4):528. doi: 10.3390/mi13040528.
3D printing, that is, additive manufacturing, has solved many major problems in general manufacturing, such as three-dimensional tissue structure, microenvironment control difficulty, product production efficiency and repeatability, etc., improved the manufacturing speed and precision of personalized bone implants, and provided a lot of support for curing patients with bone injuries. The application of 3D printing technology in the medical field is gradually extensive, especially in orthopedics. The purpose of this review is to provide a report on the related achievements of bone implants based on 3D printing technology in recent years, including materials, molding methods, optimization of implant structure and performance, etc., in order to point out the existing shortcomings of 3D printing bone implants, promote the development of all aspects of bone implants, and make a prospect of 4D printing, hoping to provide some reference for the subsequent research of 3D printing bone implants.
3D打印,即增材制造,解决了一般制造业中的许多重大问题,如三维组织结构、微环境控制难度、产品生产效率和可重复性等,提高了个性化骨植入物的制造速度和精度,为治愈骨损伤患者提供了诸多支持。3D打印技术在医疗领域的应用日益广泛,尤其是在骨科方面。本综述的目的是汇报近年来基于3D打印技术的骨植入物的相关成果,包括材料、成型方法、植入物结构与性能优化等,以指出3D打印骨植入物存在的不足,推动骨植入物各方面的发展,并对4D打印进行展望,希望能为后续3D打印骨植入物的研究提供一些参考。