Timorshina Svetlana, Popova Elizaveta, Osmolovskiy Alexander
Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Polymers (Basel). 2022 Apr 14;14(8):1601. doi: 10.3390/polym14081601.
Currently, the growth of the global population leads to an increase in demand for agricultural products. Expanding the obtaining and consumption of food products results in a scale up in the amount of by-products formed, the development of processing methods for which is becoming an urgent task of modern science. Collagen and keratin make up a significant part of the animal origin protein waste, and the potential for their biotechnological application is almost inexhaustible. The specific fibrillar structure allows collagen and keratin to be in demand in bioengineering in various forms and formats, as a basis for obtaining hydrogels, nanoparticles and scaffolds for regenerative medicine and targeted drug delivery, films for the development of biodegradable packaging materials, etc. This review describes the variety of sustainable sources of collagen and keratin and the beneficial application multiformity of these proteins.
目前，全球人口的增长导致对农产品的需求增加。食品获取和消费的扩大导致副产品形成量的增加，开发其加工方法正成为现代科学的一项紧迫任务。胶原蛋白和角蛋白构成了动物源蛋白质废料的很大一部分，它们的生物技术应用潜力几乎是无穷无尽的。特定的纤维状结构使胶原蛋白和角蛋白在生物工程中以各种形式和形态受到需求，可作为获得用于再生医学和靶向药物递送的水凝胶、纳米颗粒和支架、用于开发可生物降解包装材料的薄膜等的基础。本综述描述了胶原蛋白和角蛋白的各种可持续来源以及这些蛋白质有益的应用多样性。
