Yin Zongzhi, Li Tengteng, Zhou Lu, Fei Jiajia, Su Jingjing, Li Dan
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
Department of Obstetrics and Gynecology, Chaohu Hospital of Anhui Medical University, Chaohu, 238001, China.
BMC Pregnancy Childbirth. 2022 Apr 23;22(1):356. doi: 10.1186/s12884-022-04683-2.
To determine the optimal delivery time for women with diet-controlled gestational diabetes mellitus by comparing differences in adverse maternal-fetal outcome and cesarean section rates.
This real-world retrospective study included 1,050 patients with diet-controlled gestational diabetes mellitus who delivered at 35-42 weeks' gestation. Data on patient characteristics, maternal-fetal outcomes, and cesarean section rate based on fetal gestational age were collected and analyzed. Differences between deliveries with and without iatrogenic intervention were also analyzed.
The cesarean section rate at ≥ 41 weeks' gestation was significantly higher than that at 39-39 + 6 weeks (56% vs. 39%, p = 0.031). There were no significant differences in multiple adverse maternal or neonatal outcomes at delivery before and after 39 weeks. Vaginal delivery rates were increased significantly at 39-39 + 6 weeks due to iatrogenic intervention (p = 0.005) and 40-40 + 6 weeks (p = 0.003) in patients without and with spontaneous uterine contractions, respectively.
It's recommended that optimal delivery time for patients with diet-controlled gestational diabetes mellitus should be between 39- and 40 + 6 weeks' gestation. Patients who have Bishop scores higher than 4 can undergo iatrogenic intervention at 39-39 + 6 weeks. However iatrogenic interventions are not recommended for patients with low Bishop scores.
通过比较母婴不良结局和剖宫产率的差异,确定饮食控制的妊娠期糖尿病女性的最佳分娩时间。
这项真实世界的回顾性研究纳入了1050例在妊娠35 - 42周分娩的饮食控制的妊娠期糖尿病患者。收集并分析了患者特征、母婴结局以及基于胎儿孕周的剖宫产率数据。还分析了有无医源性干预分娩之间的差异。
妊娠≥41周时的剖宫产率显著高于39 - 39⁺⁶周时(56%对39%,p = 0.031)。39周前后分娩时母婴多种不良结局无显著差异。在无自发宫缩和有自发宫缩的患者中,医源性干预分别使39 - 39⁺⁶周(p = 0.005)和40 - 40⁺⁶周(p = 0.003)的阴道分娩率显著增加。
建议饮食控制的妊娠期糖尿病患者的最佳分娩时间应在妊娠39至40⁺⁶周之间。Bishop评分高于4分的患者可在39 - 39⁺⁶周接受医源性干预。然而,不建议Bishop评分低的患者进行医源性干预。