Iwamoto K, Schwartz H
Arch Ophthalmol. 1978 Aug;96(8):1378-9. doi: 10.1001/archopht.1978.03910060132007.
Postoperative nausea with emesis is an undesirable side effect of general anesthesia in patients who have undergone ophthalmic surgery. The antiemetic effect of intravenous droperidol (Inapsine) was measured in a double-blind, controlled study of 78 patients undergoing general (enflurane [Ethrane]) anesthesia for a variety of ophthalmic procedures. There was a significant difference in the incidence of postoperative nausea and/or emesis in the droperidol-treated group, 13 of 78 (16%) as compared with the control population (37 of 87 [42%]). No complications of droperidol administration were observed. Droperidol may be an effective antiemetic drug if used prophylactically in patients who receive general anesthesia for ophthalmic surgery.
术后恶心呕吐是眼科手术患者全身麻醉后出现的不良副作用。在一项双盲对照研究中，对78例接受全身（安氟醚[易使宁]）麻醉进行各种眼科手术的患者测定了静脉注射氟哌利多（氟哌啶）的止吐效果。氟哌利多治疗组术后恶心和/或呕吐的发生率与对照组（87例中的37例[42%]）相比有显著差异，氟哌利多治疗组78例中有13例（16%）。未观察到氟哌利多给药的并发症。如果在接受眼科手术全身麻醉的患者中预防性使用，氟哌利多可能是一种有效的止吐药物。
