Abdelrahim Maen, Esmail Abdullah, Al Saadi Noor, Zsigmond Eva, Al Najjar Ebtesam, Bugazia Doaa, Al-Rawi Hadeel, Alsaadi Ayat, Kaseb Ahmed O
Houston Methodist Cancer Center, Houston Methodist Hospital, Houston, TX, United States.
Cockrell Center for Advanced Therapeutic Phase I Program, Houston Methodist Research Institute, Houston, TX, United States.
Front Pharmacol. 2022 Apr 5;13:848676. doi: 10.3389/fphar.2022.848676. eCollection 2022.
The COVID-19 pandemic has impacted every country in the world. With more than 400 million cases and more than 5.5 million deaths. The FDA either approved or authorized the emergency use for three vaccines against COVID-19. The treatment options of COVID-19 are very limited. Multiple complementary and alternative medicine modalities were suggested to be efficacious in the treatment of COVID-19 such as Thymoquinone. The effects of Thymoquinone have been examined and multiple studies indicate a promising beneficial effect. However, the current body of research is limited in terms of its scope, quality, and quantity. While higher-quality studies are required, physicians do not routinely recommend the use of marketed supplements of natural products, including Thymoquinone for COVID-19. Given the numerous suggested positive effects of Thymoquinone, including anti-inflammatory and antimicrobial properties, additional research is required to confirm or refute these promising benefits. Complementary and alternative medicine is an area that requires additional evidence-based practice and research to confirm effects observed in clinical practice.
新冠疫情已影响到世界上的每个国家。病例超过4亿，死亡人数超过550万。美国食品药品监督管理局（FDA）已批准或授权三种新冠疫苗紧急使用。新冠的治疗选择非常有限。有人提出多种补充和替代医学方法对新冠治疗有效，比如百里醌。人们已对百里醌的效果进行了研究，多项研究表明其有有益效果。然而，目前的研究在范围、质量和数量方面都很有限。虽然需要更高质量的研究，但医生通常不会推荐使用包括百里醌在内的市售天然产品补充剂来治疗新冠。鉴于百里醌有诸多潜在积极作用，包括抗炎和抗菌特性，还需要更多研究来证实或反驳这些潜在益处。补充和替代医学领域需要更多循证实践和研究，以确认临床实践中观察到的效果。
