SARS-CoV-2 在人工海水中和无生命材料表面的存活情况。
Survival of SARS-CoV-2 in artificial seawater and on the surface of inanimate materials.
机构信息
BSL-3 laboratory of Fudan University, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, China.
Department of Medical Microbiology and Parasitology, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, China.
出版信息
J Med Virol. 2022 Aug;94(8):3982-3987. doi: 10.1002/jmv.27807. Epub 2022 May 5.
There is a potential risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread through human contact with seafood and the inanimate materials contaminated by the virus. In this study, we examined the stability of the virus in artificial seawater (ASW) and on the surface of selected materials. SARS-CoV-2 (3.75 log TCID ) in ASW at 22℃ maintained infectious about 3 days and at 4℃ the virus survived more than 7 days. It should be noticed that viable virus at high titer (5.50 log TCID ) may survive more than 20 days in ASW at 4℃ and for 7 days at 22℃. SARS-CoV-2 on stainless steel and plastic bag maintained infectious for 3 days, and on nonwoven fabric for 1 day at 22℃. In addition, the virus remained infectious for 9 days on stainless steel and non-woven fabric, and on plastic bag for 12 days at 4℃. It is important to highlight the role of inanimate material surfaces as a source of infection and the necessity for surface decontamination and disinfection.
新冠病毒（SARS-CoV-2）可能通过人类接触受病毒污染的海鲜和无生命材料而传播。在这项研究中，我们研究了病毒在人工海水中（ASW）和选定材料表面的稳定性。在 22°C 的 ASW 中，3.75 log TCID 的 SARS-CoV-2 大约能保持 3 天的传染性，而在 4°C 时，病毒的存活时间超过 7 天。值得注意的是，高滴度（5.50 log TCID）的存活病毒在 4°C 的 ASW 中可能存活超过 20 天，在 22°C 下可存活 7 天。SARS-CoV-2 在不锈钢和塑料袋上 22°C 时可保持 3 天的传染性，在无纺布袋上保持 1 天的传染性。此外，病毒在不锈钢和无纺布袋上可保持 9 天的传染性，在塑料袋上可保持 12 天的传染性。重要的是要强调无生命材料表面作为感染源的作用，以及表面去污和消毒的必要性。
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