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无并发症输尿管镜检查术后输尿管引流情况调查(支架)

Survey on ureTEric draiNage post uncomplicaTed ureteroscopy (STENT).

作者信息

Bhatt Nikita R, MacKenzie Kenneth, Shah Taimur T, Gallagher Kevin, Clement Keiran, Cambridge William A, Kulkarni Meghana, MacLennan Graeme, Manecksha Rustom P, Wiseman Oliver J, Mcclinton Samuel, Smith Daron, Kasivisvanathan Veeru

机构信息

Department of Urology Norfolk and Norwich University Hospital Norwich UK.

British Urological Researchers in Surgical Training (BURST) Collaborative.

出版信息

BJUI Compass. 2020 Oct 8;2(2):115-125. doi: 10.1002/bco2.48. eCollection 2021 Mar.

Abstract

OBJECTIVES

To assess the feasibility of conducting a randomised controlled trial (RCT) to assess whether avoiding ureteric drainage is superior to performing ureteric drainage after Uncomplicated Ureteroscopy and/or Flexible Ureterorenoscopy (URS/FURS) treatment of a urinary tract stone in improving patient reported outcome measures (PROMs) and 30-day unplanned readmission rates. A secondary objective was to understand current practice of urologists regarding ureteric drainage after uncomplicated URS/FURS (UU).

MATERIAL AND METHODS

We undertook an online survey of urologists, circulated amongst members of international urological societies and through social media platforms. Uncomplicated URS/FURS was defined as completion of URS/FURS treatment for a urinary tract stone, with the absence of: ureteral trauma, residual fragments requiring further lithotripsy procedures, significant bleeding, perforation, prior urinary tract infection or pregnancy. The ureteric drainage options considered included an indwelling stent, stent on a string or a ureteric catheter. The primary outcome was to determine the proportion of urologists willing to take part in a RCT, randomising patients after UU to a "no ureteric drainage" arm or ureteric drainage arm. Secondary outcomes included determining in their current practice, the proportion of clinicians performing routine ureteric drainage after UU, the reasons for performing ureteric drainage following UU and their preferred optimal duration for ureteric drainage if it is used. The study was reported according to the Checklist for Reporting Results of Internet E-Surveys (CHERRIES).

RESULTS

Total of 468 respondents from 45 countries took part in the survey, of whom 303 completed the entire survey (65%). The majority agreed that they would be willing to randomise patients (244/303, 81%) in the proposed RCT. Perceived lack of equipoise to randomise was the most common reason for not being willing to participate (59/303, 19%).92% (308/335) reported that they use ureteric drainage after UU. This was most often due to wanting to prevent possible complications from post-operative ureteric oedema (77%) or to aid passage of small fragments (43%). Complexity of the case (i.e. impacted stone 90%) and length of the procedure (46%) were the most important intraoperative factors influencing the decision to use ureteric drainage post procedure. If required, the median stated ideal duration of ureteric drainage was 5 days (IQR: 3-7 days) after UU. If having UU personally, 30% would want no stent postoperatively and over half would prefer a stent on a string.

CONCLUSION

We have highlighted wide variation in practice regarding ureteric drainage after UU. Our results support the feasibility of an RCT evaluating if no ureteric drainage is superior to ureteric drainage in improving PROMs and 30-day unplanned readmission rates following UU.

摘要

目的

评估开展一项随机对照试验(RCT)的可行性,以评估在单纯输尿管镜检查和/或软性输尿管肾镜检查(URS/FURS)治疗尿路结石后,不进行输尿管引流是否优于进行输尿管引流,从而改善患者报告结局指标(PROMs)和30天非计划再入院率。次要目的是了解泌尿外科医生在单纯URS/FURS(UU)后输尿管引流的当前做法。

材料与方法

我们对泌尿外科医生进行了一项在线调查,通过国际泌尿外科学会成员以及社交媒体平台进行传播。单纯URS/FURS被定义为完成尿路结石的URS/FURS治疗,且不存在以下情况:输尿管创伤、需要进一步碎石手术的残留碎片、大量出血、穿孔、既往尿路感染或妊娠。所考虑的输尿管引流选项包括留置支架、带线支架或输尿管导管。主要结局是确定愿意参与RCT的泌尿外科医生比例,该试验将UU后的患者随机分为“无输尿管引流”组或输尿管引流组。次要结局包括确定在他们当前的实践中,UU后进行常规输尿管引流的临床医生比例、UU后进行输尿管引流的原因以及如果使用输尿管引流,他们首选的最佳持续时间。该研究按照互联网电子调查结果报告清单(CHERRIES)进行报告。

结果

来自45个国家的468名受访者参与了调查,其中303人完成了全部调查(65%)。大多数人同意他们愿意在拟议的RCT中对患者进行随机分组(244/303,81%)。认为缺乏随机分组的 equipoise是不愿意参与的最常见原因(59/303,19%)。92%(308/335)报告称他们在UU后使用输尿管引流。这最常见的原因是想要预防术后输尿管水肿可能导致的并发症(77%)或帮助小碎片排出(43%)。病例的复杂性(即嵌顿结石90%)和手术时间(46%)是影响术后使用输尿管引流决策的最重要术中因素。如果需要,输尿管引流的中位理想持续时间为UU后5天(IQR:3 - 7天)。如果自己接受了UU,30%的人术后不想放置支架,超过一半的人更喜欢带线支架。

结论

我们强调了UU后输尿管引流在实践中的广泛差异。我们的结果支持了一项RCT的可行性,该RCT评估在改善PROMs和UU后的30天非计划再入院率方面,不进行输尿管引流是否优于输尿管引流。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1ea/8988693/973e0bf675f5/BCO2-2-115-g003.jpg

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