Reproductive Health Research Center, Department of Obstetrics and Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box: 4144654839, Rasht, Iran.
BMC Womens Health. 2022 Apr 27;22(1):136. doi: 10.1186/s12905-022-01715-z.
During menopause, women experience annoying symptoms which may affect their daily activities and quality of life. This study aimed to determine whether reproductive history, an important indicator of estrogen exposure across the lifetime, is associated with the severity of menopausal symptoms in women.
This study was a cross-sectional study conducted on 214 women aged 35-65 who were randomly selected, and data was collected by a predesigned structured questionnaire. Each item was graded by subjects and a total score was obtained by summing all subscale scores.
There was a significant association between the somatic, psychological, and urogenital menopausal symptoms and reproductive characteristics. Women with a history of abortion had greater total (β = 0.194, p = 0.009), and psychological (β = 0.230, p = 0.002) symptoms score. Women with higher number of children were more likely to have higher somatic (β = 0.212, p = 0.005) symptoms than others.
Our findings showed reproductive factors may have an influence on the severity of menopausal symptoms. After confirmation by further studies, these findings may help target women at risk of more severe menopausal symptoms at later ages.
在绝经期，女性会经历一些烦人的症状，这些症状可能会影响她们的日常活动和生活质量。本研究旨在确定生殖史（一生中雌激素暴露的一个重要指标）是否与女性绝经期症状的严重程度有关。
这是一项横断面研究，共纳入 214 名年龄在 35-65 岁之间的随机女性，通过预先设计的结构化问卷收集数据。每个项目由受试者评分，通过将所有子量表的得分相加得出总分。
躯体、心理和泌尿生殖系统的绝经期症状与生殖特征之间存在显著关联。有流产史的女性总（β=0.194，p=0.009）和心理（β=0.230，p=0.002）症状评分更高。生育子女数量较多的女性躯体症状评分（β=0.212，p=0.005）也更高。
我们的研究结果表明，生殖因素可能对绝经期症状的严重程度有影响。进一步的研究证实后，这些发现可能有助于针对晚年出现更严重绝经期症状风险较高的女性。
