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The discovery of type IV interferon system revolutionizes interferon family and opens up a new frontier in jawed vertebrate immune defense.IV型干扰素系统的发现彻底改变了干扰素家族,并为有颌脊椎动物的免疫防御开辟了一个新领域。
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Interferon Complex: Inscribing the Amphibiotic Adaption and Species-Specific Pathogenic Pressure in Vertebrate Evolution?干扰素复合物:在脊椎动物进化中刻写两栖动物适应和物种特异性致病压力?
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IFN-γ2 enhances proliferation and differentiation of muscle cells: a novel target of natural grass feeding mode improving muscle quality in grass carp (Ctenopharyngodon idella).干扰素-γ2增强肌肉细胞的增殖和分化:天然草料喂养模式改善草鱼(Ctenopharyngodon idella)肌肉品质的新靶点。
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Transcriptional regulation and signaling of type IV interferon in Carassius gibelio.异育银鲫IV型干扰素的转录调控与信号传导
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Genome-wide identification of the interferon complex establishes IFNf in Cypriniformes.全基因组范围内对干扰素复合物的鉴定确定了鲤形目鱼类中的IFNf。
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Anti-infective immune functions of type IV interferon in grass carp ( ): A novel antibacterial and antiviral interferon in lower vertebrates.草鱼中IV型干扰素的抗感染免疫功能( ): 一种低等脊椎动物中的新型抗菌和抗病毒干扰素
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Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection.干扰素在抗病毒斗争中的作用:从病毒-宿主相互作用到 SARS-CoV-2 感染的预防和治疗潜力。
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TLR7 neo-functionalizes to sense dsRNA and trigger antiviral and antibacterial immunity in non-tetrapod vertebrates.Toll样受体7(TLR7)发生新功能化,以识别双链RNA并触发非四足脊椎动物的抗病毒和抗菌免疫。
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The Combination of β-Glucan and Astragalus Polysaccharide Effectively Resists Infection in Largemouth Bass ().β-葡聚糖与黄芪多糖联合使用可有效抵抗大口黑鲈感染( )。
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VP4/VP56/VP35 Virus-like Particles Effectively Protect Grass Carp () against GCRV-II Infection.VP4/VP56/VP35病毒样颗粒有效保护草鱼抵抗GCRV-II感染。
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本文引用的文献

1
Identification and establishment of type IV interferon and the characterization of interferon-υ including its class II cytokine receptors IFN-υR1 and IL-10R2.鉴定和建立 IV 型干扰素,并对干扰素-υ(包括其 II 类细胞因子受体 IFN-υR1 和 IL-10R2)进行特征描述。
Nat Commun. 2022 Feb 22;13(1):999. doi: 10.1038/s41467-022-28645-6.
2
Broad-Spectrum Robust Direct Bactericidal Activity of Fish IFNφ1 Reveals an Antimicrobial Peptide-like Function for Type I IFNs in Vertebrates.广谱稳健的鱼类 IFNφ1 直接杀菌活性揭示了脊椎动物 I 型干扰素的抗菌肽样功能。
J Immunol. 2021 Mar 15;206(6):1337-1347. doi: 10.4049/jimmunol.2000680. Epub 2021 Feb 10.
3
Fish TNF and TNF receptors.鱼类肿瘤坏死因子和肿瘤坏死因子受体。
Sci China Life Sci. 2021 Feb;64(2):196-220. doi: 10.1007/s11427-020-1712-4. Epub 2020 Jul 24.
4
Evolution of Interferons and Interferon Receptors.干扰素和干扰素受体的进化
Front Immunol. 2017 Mar 2;8:209. doi: 10.3389/fimmu.2017.00209. eCollection 2017.

The discovery of type IV interferon system revolutionizes interferon family and opens up a new frontier in jawed vertebrate immune defense.

作者信息

Su Jianguo

机构信息

Department of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.

Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology, Qingdao, 266237, China.

出版信息

Sci China Life Sci. 2022 Nov;65(11):2335-2337. doi: 10.1007/s11427-022-2112-0. Epub 2022 Apr 25.

DOI:10.1007/s11427-022-2112-0
PMID:35484446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9050481/
Abstract
摘要