与 COVID-19 感染相关的新发狼疮性肾炎。
New-onset lupus nephritis associated with COVID-19 infection.
机构信息
1466Johns Hopkins University, Baltimore, MD, USA.
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Lupus. 2022 Jul;31(8):1007-1011. doi: 10.1177/09612033221098571. Epub 2022 Apr 29.
Abstract
A dysregulated immune response plays a critical role in systemic lupus erythematosus (SLE) pathogenesis. Environmental factors such as viruses, including coronavirus 2 (COVID-19), have been described to play a role in SLE presentation and exacerbation. These viruses trigger a host's humoral and cellular immunities typically essential in elimination of the viral infection. We present a case of a Hispanic male who developed new-onset lupus nephritis class II after a COVID-19 infection.
摘要
免疫失调在系统性红斑狼疮（SLE）发病机制中起着关键作用。环境因素如病毒，包括冠状病毒 2（COVID-19），已被描述为在 SLE 的表现和恶化中起作用。这些病毒引发宿主的体液和细胞免疫，这通常是消除病毒感染所必需的。我们报告了一例西班牙裔男性在 COVID-19 感染后发生新诊断的狼疮肾炎 II 级的病例。
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