Walker-Caprioglio H M, Parks L W
Appl Environ Microbiol. 1987 Jan;53(1):33-5. doi: 10.1128/aem.53.1.33-35.1987.
Viable Saccharomyces cerevisiae suspended in medium containing growth-inhibiting concentrations of ethanol produce a metabolite that relieves growth inhibition. This autoconditioning of the medium by yeasts is due to the formation of small amounts (0.01%, vol/vol) of acetaldehyde. The effect is duplicated precisely in fresh medium by the addition of acetaldehyde. Acetaldehyde does not increase the yield of or accelerate ethanol production by the organism. Ethanol-induced modifications of membrane order in the plasma membranes, as measured by steady-state fluorescence anisotropy of 1,6-diphenyl-1,3,5-hexatriene, were not resolved by exogenously added acetaldehyde.
悬浮于含有抑制生长浓度乙醇的培养基中的活酿酒酵母会产生一种代谢物，该代谢物可缓解生长抑制。酵母对培养基的这种自身调节作用是由于形成了少量（0.01%，体积/体积）的乙醛。通过添加乙醛，可在新鲜培养基中精确重现该效应。乙醛不会提高该生物体的乙醇产量，也不会加速其乙醇生成。通过1,6-二苯基-1,3,5-己三烯的稳态荧光各向异性测量，乙醇诱导的质膜中膜有序性的改变并未因外源添加乙醛而得到解决。
