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[针刺治疗缺血性中风的机制:综述]

[Mechanism of acupuncture in treatment of ischemic stroke: a review].

作者信息

Yao Jia-Yong, Zou Wei

机构信息

Heilongjiang University of Chinese Medicine, Harbin 150040, China.

The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040.

出版信息

Zhen Ci Yan Jiu. 2022 Apr 25;47(4):354-61. doi: 10.13702/j.1000-0607.20210426.

DOI:10.13702/j.1000-0607.20210426
PMID:35486016
Abstract

Acupuncture can intervene in and treat ischemic stroke (IS) through multiple targets and pathways. In recent years, experimental studies have shown that the mechanism of acupuncture in the treatment of IS mainly involves the promotion of nerve repair and regeneration, the regulation of the activity of neurotransmitters, the improvement of cerebral blood flow, the alleviation of brain edema, the reduction of oxidative stress, the inhibition of apoptosis and autophagy, and the suppression of inflammatory responses. This paper reviewed the available mechanisms of acupuncture in the treatment of IS to provide theoretical support for the clinical application of acupuncture against IS and references for further research.

摘要

针灸可通过多个靶点和途径干预和治疗缺血性中风(IS)。近年来,实验研究表明,针灸治疗IS的机制主要涉及促进神经修复和再生、调节神经递质活性、改善脑血流量、减轻脑水肿、降低氧化应激、抑制细胞凋亡和自噬以及抑制炎症反应。本文综述了针灸治疗IS的现有机制,为针灸临床治疗IS提供理论支持,并为进一步研究提供参考。

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Medicine (Baltimore). 2025 Jan 10;104(2):e41075. doi: 10.1097/MD.0000000000041075.
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Electroacupuncture Downregulating Neuronal Ferroptosis in MCAO/R Rats by Activating Nrf2/SLC7A11/GPX4 Axis.电针对 MCAO/R 大鼠神经元铁死亡的调控作用及其机制研究。
Neurochem Res. 2024 Aug;49(8):2105-2119. doi: 10.1007/s11064-024-04185-x. Epub 2024 May 31.