Tao Miao-Miao, Cheng Ai-Fang, Zhang Ying-Jie, Deng Yun-Yi, Xu Ming-Shu
Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China.
Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China; Shanghai Research Institute of Acupuncture and Meridian, Shanghai 200030.
Zhen Ci Yan Jiu. 2022 Jun 25;47(6):553-8. doi: 10.13702/j.1000-0607.20210526.
Acupuncture has an unique advantage in treatment of ischemic stroke, which not only promotes the repair of synaptic structure and function, but also regulates the transmission of neurotransmitters and receptors, as well as induces glial cell to repair neurons, and then to protect them. At present, the mechanism study on acupuncture for advancing synaptic plasticity in cerebral ischemia is of the high priority. In the paper, from the following three aspects, i.e. synaptic plasticity (structure and function), interaction between synapses (neurotransmitters and receptors), and interconnection between synapses and environments (synaptic-glial structure), the progress of mechanism study of acupuncture in recent years was reviewed on regulating synaptic plasticity in treatment of ischemic stroke.
针刺在缺血性脑卒中治疗中具有独特优势，不仅能促进突触结构和功能的修复，还能调节神经递质和受体的传递，诱导胶质细胞修复神经元并保护它们。目前，针刺促进脑缺血突触可塑性的机制研究具有高度优先性。本文从突触可塑性（结构和功能）、突触间相互作用（神经递质和受体）、突触与环境的相互联系（突触-胶质结构）这三个方面，对近年来针刺治疗缺血性脑卒中调节突触可塑性的机制研究进展进行了综述。
