De Silva L M, Khan M S, Kampfner G, Tobin J O, Gillett R, Morris C A
J Hyg (Lond). 1973 Mar;71(1):107-12. doi: 10.1017/s002217240004626x.
Necropsy blood from cases diagnosed as dying from influenza A was examined for specific antibody in the IgG, IgA and IgM fractions and a specific diagnosis of recent infection was made if either IgM or IgA antibody and low titres of IgG antibody were found. By these criteria a diagnostic rate of 77% was found in those cases from whom no virus was isolated. The use of infected cell monolayers grown on polytetrafluoroethylene-coated slides gave a simple method of carrying out these antibody assays, and the use of necropsy blood did not require any special methods of transport of specimens to the virus laboratory.
对诊断为死于甲型流感的病例的尸检血液进行了IgG、IgA和IgM组分中特异性抗体的检测。如果发现IgM或IgA抗体以及低滴度的IgG抗体，则可做出近期感染的特异性诊断。根据这些标准，在未分离出病毒的病例中诊断率为77%。在涂有聚四氟乙烯的载玻片上生长感染细胞单层，为进行这些抗体检测提供了一种简单方法，而且使用尸检血液不需要将标本运送到病毒实验室的任何特殊方法。
