成人青光眼患者在贡德尔大学综合专科医院就诊时间延迟的决定因素。病例对照研究。

Determinants for late presentation of glaucoma among adult glaucomatous patients in University of Gondar Comprehensive Specialized Hospital. Case-control study.

机构信息

Department of Ophthalmology and Optometry, School of Medicine, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Department of of Optometry, School of Medicine, College of Medicine and Health Sciences and Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.

出版信息

PLoS One. 2022 Apr 29;17(4):e0267582. doi: 10.1371/journal.pone.0267582. eCollection 2022.

DOI:10.1371/journal.pone.0267582

PMID:35486608

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9053799/

Abstract

INTRODUCTION

Glaucoma is a disease which causes optic nerve damage and remains a major public health concern worldwide. Late presentation is a major risk factor for glaucoma induced blindness. The aim of this study was to assess determinants for late presentation of glaucoma among adult glaucomatous patients.

METHODS

A hospital-based case-control study was conducted among 452 adult glaucomatous patients. Late presenters were glaucoma patients diagnosed with cup to disc ratio (CDR) > 0.8 and mean deviation of greater than -14 decibel in either of the eyes at their first presentation. Study participants were selected among glaucomatous follow-up patients by using systematic random sampling. Data were entered into EPI Info version 7 and exported to SPSS version 22 for analysis. Bivariable and multivariable logistic regression analysis was done to identify determinants. Variables with P-value < 0.05 were considered as statistically significant.

RESULT

The mean age of participants were 55.1 ± 13.2 years. Being > 60 years of age, 4.51 times (AOR: 4.51; 95% CI: 1.74, 11.67), resided > 53 km away from the hospital 6.02 times (AOR: 6.02; 2.76, 13.14), Presenting IOP > 30 mmHg, 4.49 times (AOR: 4.49, 95% CI: 2.10, 9.12), poor knowledge of glaucoma, 4.46 times (AOR: 4.46, CI: 2.62, 7.58) and absence of regular eye checkup, 2.35 times (AOR: 2.35, 95% CI: 1.09, 5.47) higher odds of being late presenter.

CONCLUSION

Increasing age, high IOP, poor knowledge of glaucoma, residing far away from the hospital and absence of regular eye checkups were significantly associated with late presentation.

摘要

简介

青光眼是一种导致视神经损伤的疾病，仍然是全球范围内的一个主要公共卫生问题。就诊延迟是导致青光眼致盲的一个主要危险因素。本研究旨在评估成年青光眼患者就诊延迟的决定因素。

方法

这是一项在 452 名成年青光眼患者中进行的基于医院的病例对照研究。就诊延迟的患者是指首次就诊时双眼杯盘比（CDR）>0.8 和平均偏差大于-14 分贝的青光眼患者。研究参与者是通过系统随机抽样从青光眼随访患者中选择的。数据输入 EPI Info 版本 7 并导出到 SPSS 版本 22 进行分析。进行单变量和多变量逻辑回归分析以确定决定因素。P 值<0.05 的变量被认为具有统计学意义。

结果

参与者的平均年龄为 55.1±13.2 岁。年龄>60 岁，患病风险增加 4.51 倍（OR：4.51；95%CI：1.74，11.67）；居住地距离医院>53 公里，患病风险增加 6.02 倍（OR：6.02；2.76，13.14）；就诊时眼压>30mmHg，患病风险增加 4.49 倍（OR：4.49；95%CI：2.10，9.12）；对青光眼的知识了解不足，患病风险增加 4.46 倍（OR：4.46；95%CI：2.62，7.58）；未定期进行眼部检查，患病风险增加 2.35 倍（OR：2.35；95%CI：1.09，5.47）。