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内脏脂肪组织对中老年人群健康问题发展的影响及其与血清生化参数的关系:一项文献综述

Visceral Adipose Tissue Influence on Health Problem Development and Its Relationship with Serum Biochemical Parameters in Middle-Aged and Older Adults: A Literature Review.

作者信息

Moreira Vanessa C, Silva Calliandra M S, Welker Alexis F, da Silva Izabel C R

机构信息

Health Sciences and Technologies, University of Brasilia, Zip-Code: 72220-275, Brasilia, Brazil.

出版信息

J Aging Res. 2022 Apr 19;2022:8350527. doi: 10.1155/2022/8350527. eCollection 2022.

Abstract

BACKGROUND

The amount of visceral adipose tissue (VAT) tends to increase with age and is associated with several health problems, such as cardiometabolic diseases, increased infections, and overall mortality.

OBJECTIVES

This review provides a general assessment of how visceral adiposity correlates with the development of health problems and changes in serum biochemical parameters in middle-aged and older adults.

METHODS

We searched specific terms in the Virtual Health Library (VHL) databases for VAT articles published in the English language between 2009 and 2019 related to older adults.

RESULTS

The search found twenty-three publications in this period, of which nine were excluded. The publications had a population aged between 42 and 83 years and correlated the VAT area ratio with several comorbidities (such as pancreatitis, depression, cancer, and coronary heart disease) and serum biochemical parameters.

CONCLUSION

Further research on the association between visceral obesity and the emergence of health problems and the relationship between VAT and changes in serum biochemical parameters in older individuals should deepen the understanding of this connection and develop preventive actions.

摘要

背景

内脏脂肪组织(VAT)的量往往会随着年龄增长而增加,并与多种健康问题相关,如心脏代谢疾病、感染增加和全因死亡率上升。

目的

本综述对中年及老年人群中内脏肥胖与健康问题的发生以及血清生化参数变化之间的相关性进行了综合评估。

方法

我们在虚拟健康图书馆(VHL)数据库中搜索了2009年至2019年间以英文发表的与老年人相关的VAT文章的特定术语。

结果

该搜索在此期间共找到23篇出版物,其中9篇被排除。这些出版物的研究对象年龄在42岁至83岁之间,并将VAT面积比与多种合并症(如胰腺炎、抑郁症、癌症和冠心病)以及血清生化参数进行了关联。

结论

关于内脏肥胖与健康问题出现之间的关联以及老年人中VAT与血清生化参数变化之间的关系的进一步研究,应能加深对这种联系的理解并制定预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2cd/9042620/4c77b1a6ae9d/JAR2022-8350527.001.jpg

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