使用手性氨基亚磷酸酯钌配合物的对映选择性和区域选择性不对称烯丙基取代：实验与理论研究

Enantio- and regioselective asymmetric allylic substitution using a chiral aminophosphinite ruthenium complex: an experimental and theoretical investigation.

作者信息

Jena Rajesh K, Das Dhiraj

机构信息

Centre of Excellence in Advanced Materials and Applications, Utkal University, Vani Vihar Bhubaneswar-751004 India

Department of Chemistry, Indian Institute of Technology Kharagpur Kharagpur 721302 India.

出版信息

RSC Adv. 2021 Dec 9;11(62):39319-39327. doi: 10.1039/d1ra06824e. eCollection 2021 Dec 6.

The design and synthesis of a new chiral aminophosphinite-ligated ruthenium complex is described. The ruthenium complex, [Ru(AMP)(CHCN)][BPh] {AMP = ()--butyl 1-(diphenylphosphinooxy)-3-methylbutan-2-ylcarbamate}, has been found to catalyze nucleophilic addition of phenol and carboxylic acid to allyl chloride in a highly regioselective fashion with enantiomeric excess ranging from 12 to 90.